Do “central sensitization” questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses

GR Adams, W Gandhi, R Harrison, CM Van Reekum… - Pain, 2023 - journals.lww.com
Central sensitization (CS) is defined as an increased nociceptive responsiveness due to
sensitization of neurons in the central nervous system, usually the result of prolonged …

Is chronic pain caused by central sensitization? A review and critical point of view

E Velasco, M Flores-Cortes, J Guerra-Armas… - Neuroscience & …, 2024 - Elsevier
Chronic pain causes disability and loss of health worldwide. Yet, a mechanistic explanation
for it is still missing. Frequently, neural phenomena, and among them, Central Sensitization …

Reductions in kinesiophobia and distress after pain neuroscience education and exercise lead to favourable outcomes: a secondary mediation analysis of a …

C Murillo, MÁ Galán-Martín, F Montero-Cuadrado… - Pain, 2023 - journals.lww.com
2. Methods This is a secondary analysis of a previously published randomized controlled
trial (RCT) 21 in patients with chronic spinal pain in primary care. This mediation analysis …

[PDF][PDF] Central sensitivity in fibromyalgia: testing a model to explain the role of psychological factors on functioning and quality of life

FM Nimbi, A Renzi, E Limoncin… - Clin Exp …, 2024 - clinexprheumatol.org
Objective Central sensitivity (CS) is defined as an increased responsiveness of nociceptive
neurons in the central nervous system to normal or subthreshold inputs. CS has recently …

A systematic review and meta-analysis of questionnaires to screen for pain sensitisation and neuropathic like pain in inflammatory arthritis

Z Rutter-Locher, N Arumalla, S Norton… - Seminars in Arthritis and …, 2023 - Elsevier
Background Targeted pain relief is a major unmet medical need for patients with
inflammatory arthritis (IA), where approximately 40% of patients experience persistent pain …

A manifesto in defense of pain complexity: a critical review of essential insights in pain neuroscience

JP Párraga, A Castellanos - Journal of Clinical Medicine, 2023 - mdpi.com
Chronic pain has increasingly become a significant health challenge, not just as a
symptomatic manifestation but also as a pathological condition with profound …

Association of central sensitization inventory scores with pain outcomes after endometriosis surgery

NL Orr, AJ Huang, YD Liu, H Noga… - JAMA Network …, 2023 - jamanetwork.com
Importance A subset of people who undergo surgery for endometriosis have persistent pain,
suggesting that other factors besides the endometriosis, such as central sensitization, may …

Sleep quality mediates the effect of sensitization-associated symptoms, anxiety, and depression on quality of life in individuals with post-COVID-19 pain

JC Pacho-Hernández, C Fernández-de-Las-Peñas… - Brain Sciences, 2022 - mdpi.com
A better understanding of biological and emotional variables associated with health-related
quality of life in people with long-COVID is needed. Our aim was to identify potential direct …

Sensitization symptoms are associated with psychological and cognitive variables in COVID‐19 survivors exhibiting post‐COVID pain

C Fernández‐de‐las‐Peñas, P Parás‐Bravo… - Pain …, 2023 - Wiley Online Library
Objective To investigate the association between demographic, clinical, psychological,
cognitive, and health‐related variables and the Central Sensitization Inventory (CSI) in …

Central sensitization in cancer survivors and its clinical implications: state of the art

T Nishigami, M Manfuku, A Lahousse - Journal of Clinical Medicine, 2023 - mdpi.com
Although the prevalence of cancer pain is 47% after treatment, cancer pain is often
underestimated, and many patients are undertreated. The complexity of cancer pain …