The mucosal immune system of fish: the evolution of tolerating commensals while fighting pathogens
The field of mucosal immunology research has grown fast over the past few years, and our
understanding on how mucosal surfaces respond to complex antigenic cocktails is …
understanding on how mucosal surfaces respond to complex antigenic cocktails is …
An overview of the immunological defenses in fish skin
M Ángeles Esteban - International scholarly research notices, 2012 - Wiley Online Library
The vertebrate immune system is comprised of numerous distinct and interdependent
components. Every component has its own inherent protective value, and the final …
components. Every component has its own inherent protective value, and the final …
The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host–microbial interactions
MEV Johansson, JMH Larsson… - Proceedings of the …, 2011 - National Acad Sciences
The normal intestinal microbiota inhabits the colon mucus without triggering an inflammatory
response. The reason for this and how the intestinal mucus of the colon is organized have …
response. The reason for this and how the intestinal mucus of the colon is organized have …
The role of the gastrointestinal mucus system in intestinal homeostasis: implications for neurological disorders
Mucus is integral to gut health and its properties may be affected in neurological disease.
Mucus comprises a hydrated network of polymers including glycosylated mucin proteins. We …
Mucus comprises a hydrated network of polymers including glycosylated mucin proteins. We …
Composition and functional role of the mucus layers in the intestine
MEV Johansson, D Ambort, T Pelaseyed… - Cellular and molecular …, 2011 - Springer
In discussions on intestinal protection, the protective capacity of mucus has not been very
much considered. The progress in the last years in understanding the molecular nature of …
much considered. The progress in the last years in understanding the molecular nature of …
The densely O-glycosylated MUC2 mucin protects the intestine and provides food for the commensal bacteria
All mucins are highly O-glycosylated by variable glycans depending on species, histoblood
group and organ. This makes the intestinal main mucin MUC2 non-degradable by the host …
group and organ. This makes the intestinal main mucin MUC2 non-degradable by the host …
Revealing the human mucinome
Mucin domains are densely O-glycosylated modular protein domains found in various
extracellular and transmembrane proteins. Mucin-domain glycoproteins play important roles …
extracellular and transmembrane proteins. Mucin-domain glycoproteins play important roles …
Gel-forming mucins appeared early in metazoan evolution
T Lang, GC Hansson… - Proceedings of the …, 2007 - National Acad Sciences
Mucins are proteins that cover and protect epithelial cells and are characterized by domains
rich in proline, threonine, and serine that are heavily glycosylated (PTS or mucin domains) …
rich in proline, threonine, and serine that are heavily glycosylated (PTS or mucin domains) …
Membrane mucins of the intestine at a glance
Membrane mucins cover most mucosal surfaces throughout the human body. The intestine
harbors complex population of microorganisms (the microbiota) and numerous exogenous …
harbors complex population of microorganisms (the microbiota) and numerous exogenous …
Searching the evolutionary origin of epithelial mucus protein components—mucins and FCGBP
T Lang, S Klasson, E Larsson… - Molecular biology …, 2016 - academic.oup.com
The gel-forming mucins are large glycosylated proteins that are essential components of the
mucus layers covering epithelial cells. Using novel methods of identifying mucins based on …
mucus layers covering epithelial cells. Using novel methods of identifying mucins based on …