Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

The electromechanical function of the heart involves complex, coordinated activity over time
and space. Life-threatening cardiac arrhythmias arise from asynchrony in these space–time …

Small animals support a wide range of pathological phenotypes and genotypes as versatile,
affordable models for pathogenesis of cardiovascular diseases and for exploration of …

Optogenetics is an elegant approach of precisely controlling and monitoring the biological
functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution …

Background: Studies have shown that left stellate ganglion (LSG) suppression protects
against ventricular arrhythmias (VAs). Optogenetics is a novel technique to reversibly …

This study reports the realization of an optical cochlear implant (oCI) with optimized
thermomechanical properties for optogenetic experiments. The oCI probe comprises 144 …

Optogenetic techniques permit studies of excitable tissue through genetically expressed
light-gated microbial channels or pumps permitting transmembrane ion movement. Light …

Precision medicine calls for high demand of continuous, closed-loop physiological
monitoring and accurate control, especially for cardiovascular diseases. Cardiac …

Hypertrophic cardiomyopathy (HCM) is a common inherited monogenic disease with a
prevalence of 1/500 in the general population, representing an important cause of …

Aims The primary goal in the treatment of symptomatic atrial fibrillation/flutter (AF) is to
restore sinus rhythm by cardioversion. Electrical shocks are highly effective, but have to be …