The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …

The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

In recent years, many attempts have been made to enhance the drug bioavailability and
therapeutic effectiveness of oral dosage forms. In this context, various gastroretentive drug …

There have been many efforts to improve oral drug bioavailability and therapeutic efficacy
and patient compliance. A variety of controlled-release oral delivery systems have been …

The breakthrough of 3D printing in biomedical research has paved the way for the next
evolutionary step referred to as four dimensional (4D) printing. This new concept utilizes the …

Therapy for Parkinson's disease is quite challenging. Numerous drugs are available for
symptomatic treatment, and levodopa (LD), in combination with a dopa decarboxylase …

Peptic ulcer disease (PUD) is one of the most prevalent gastro intestinal disorder which
often leads to painful sores in the stomach lining and intestinal bleeding. Untreated …

More than 50 years ago, the first concepts for gastroretentive drug delivery systems were
developed. Despite extensive research in this field, there is no single formulation concept for …

Targeting the release of drugs in specific sites of the upper GI tract would meet local
therapeutic goals, improve the bioavailability of specific drugs and help overcoming …

Floating gastro-retentive delivery systems can prolong the gastric residence providing
sustained drug release. In this study, we report on self-inflating effervescence-based …