Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Pregnancy is a unique condition where the maternal immune system is continuously
adapting in response to the stages of fetal development and signals from the environment …

The limited host tropism of numerous viruses causing disease in humans remains
incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has …

Lipid droplets (LDs) are dynamic lipid storage organelles that can be degraded by
autophagy machinery to release neutral lipids, a process called lipophagy. However …

The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global
public health crisis since 2015. ZIKV preferentially infects and targets human neural …

Most cells respond to viral infections by activating innate immune pathways that lead to the
induction of antiviral restriction factors. One such factor, viperin, was discovered almost two …

Zika virus (ZIKV) is a major public health concern in the Americas. We report that ZIKV
infection and RNA extracted from ZIKV infected cells potently activated the induction of type I …

In the ongoing conflict between eukaryotic cells and pathogens, lipid droplets (LDs) emerge
as a choke point in the battle for nutrients. While many pathogens seek the lipids stored in …

Flaviviruses are arthropod-borne viruses that constitute a major global health problem, with
millions of human infections annually. Their pathogenesis ranges from mild illness to severe …

Antiviral restriction factors are cellular proteins that inhibit the entry, replication, or spread of
viruses. These proteins are critical components of the innate immune system and function to …