Photothermal therapy (PTT) has received increasing attention due to its high selectivity, non-
invasiveness, negligible drug resistance, oxygen independence, and minimal side effects. In …

The inactivation of programmed cell death, or apoptosis, is central to the development of
cancer. This disabling of apoptotic responses might be a major contributor both to treatment …

Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …

Inherited and somatic mutations in the adenomatous polyposis coli occur in most colon
cancers, leading to activation of β-catenin-responsive genes. To identify small molecule …

The cell cycle represents a series of tightly integrated events that allow the cell to grow and
proliferate. Critical parts of the cell cycle machinery are the cyclin-dependent kinases …

Taxol®, an antitumor drug with significant activity, is the first microtubule stabilizing agent
described in the literature. This short review of the mechanism of action of Taxol® …

Apoptosis has been accepted as a fundamental component in the pathogenesis of cancer,
in addition to other human diseases including neurodegeneration, coronary disease and …

DNA damage, chromosomal abnormalities, oncogene activation, viral infection, substrate
detachment and hypoxia can all trigger apoptosis in normal cells. However, cancer cells …

Apoptosis, the cell's intrinsic death program, is a key regulator of tissue homeostasis. An
imbalance between cell death and proliferation may result in tumor formation. Also, killing of …

Various accumulating evidence suggests that survivin, a member of the inhibitor of
apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in …