The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Asthma is characterized by mucus abnormalities. Airway epithelial hyperplasia and
metaplasia result in changes in stored and secreted mucin and the production of a …

Omentin‐1, also known as intelectin‐1, is a recently identified novel adipocytokine of 313
amino acids, which is expressed in visceral (omental and epicardial) fat as well as …

The glycans displayed on mammalian cells can differ markedly from those on microbes.
Such differences could, in principle, be'read'by carbohydrate-binding proteins, or lectins. We …

Gene expression for MUC5AC is increased in airway epithelial cells in asthma, and MUC5B
expression is decreased (1, 2), but it is uncertain how this abnormal gene expression for gel …

Background Eosinophilic duodenitis (EoD), characterized by nonspecific gastrointestinal
symptoms and increased numbers of duodenal eosinophils, may be in the eosinophilic …

The epithelial and epidermal innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin
(TSLP) have pivotal roles in the initiation of allergic inflammation in asthma and atopic …

Recognition of distinct glycans is central to biology, and lectins mediate this function. Lectin
glycan preferences are usually centered on specific monosaccharides. In contrast, human …

Adiponectin is an adipokine associated with the healthy obese phenotype. Adiponectin
increases insulin sensitivity and has cardio and vascular protection actions. Studies related …

Adipokines, secreted by the adipose tissue, are extensively involved in the regulation and
maintenance of various physiological and pathological processes, including insulin …