The SLC3A2 gene encodes for a cell-surface transmembrane protein CD98hc (4F2).
CD98hc serves as a chaperone for LAT1 (SLC7A5), LAT2 (SLC7A8), y+ LAT1 (SLC7A7), y+ …

Protein tyrosine phosphatase receptor type J (PTPRJ), also known as DEP-1, HPTPη, or
CD148, belongs to the R3 subfamily of receptor protein tyrosine phosphatases (RPTPs). It …

The type II glycoprotein CD98 (SLC3A2) is a membrane protein with pleiotropic roles in
cells, ranging from modulation of inflammatory processes, host–pathogen interactions to …

Ban‐**a‐**e‐**n‐Tang (BXXXT) is a classical formula from Shang‐Han‐Lun which is one of
the earliest books of TCM clinical practice. In this work, we investigated the therapeutic …

Solute carriers form one of three major superfamilies of membrane transporters in humans,
and include uniporters, exchangers and symporters. Following several decades of …

The occurrence and development of tumors involve a series of life activities of cells, among
which cell death has always been a crucial part in the research of tumor mechanisms and …

l‐Type amino acid transporter 1 (LAT 1) disulfide linked to CD 98 heavy chain (hc) is highly
expressed in most cancer cells, but weakly expressed in normal cells. In the present study …

L-type amino acid transporter 1 (LAT1)/SLC7A5 is the first identified CD98 light chain
disulfide linked to the CD98 heavy chain (CD98hc/SLC3A2). LAT1 transports large neutral …

We investigated the concordance of mitochondrial DNA heteroplasmic mutations
(heteroplasmies) in 6745 maternal pairs of European (EA, n= 4718 pairs) and African (AA …

Central insulin resistance has been linked to the development of neurodegenerative
diseases and mood disorders. Various proteins belonging to the enzyme family of protein …