Background Skin being the largest organ of the human body plays a very important role in
the permeation and penetration of the drug. In addition, the transdermal drug delivery …

Optimisation of drug delivery through human skin is important in modern therapy. This
review considers drug–vehicle interactions (drug or prodrug selection, chemical potential …

The barrier function of skin and the non-optimal physicochemical properties of drugs present
challenges to the skin penetration of many drugs, thus motivating the development of novel …

The poor penetration of drugs into the skin (and, partially, the permeation across the stratum
corneum) often limits the efficacy of topical formulations. Basically, skin penetration can be …

To evaluate the potential use of solid lipid nanoparticles (SLN) in dermatology and
cosmetics, glyceryl behenate SLN loaded with vitamin A (retinol and retinyl palmitate) and …

Methicillin-resistant Staphylococcus aureus (MRSA) is a prevailing bacterial pathogen
linked to superficial skin and soft tissue infections (SSTIs). Rifampicin (RIF), a potent …

Tape strip** is a simple and efficient method for the assessment of quality and efficacy of
cosmetical and dermatological formulations. After topical application and penetration of …

Ethosomes are noninvasive delivery carriers that enable drugs to reach the deep skin layers
and/or the systemic circulation. Although ethosomal systems are conceptually sophisticated …

We evaluated the effect of hydrodynamic size of self-assembled nanoparticles on skin
penetration of minoxidil in vitro and in vivo. Self-assembled 40-and 130-nm nanoparticles …

The important role of hair follicles as penetration pathways and reservoir structures for
topically applied compounds has been validated in numerous animal models as well as in …