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Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression
The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …
Cortical excitability and plasticity in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis of transcranial magnetic stimulation …
Background Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation
technique. When stimulation is applied over the primary motor cortex and coupled with …
technique. When stimulation is applied over the primary motor cortex and coupled with …
Neurophysiological biomarkers using transcranial magnetic stimulation in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis
Transcranial magnetic stimulation (TMS) is a non-invasive neurophysiological tool that
enables the investigation of cortical excitability in the human brain. Paired-pulse TMS …
enables the investigation of cortical excitability in the human brain. Paired-pulse TMS …
Epilepsy and Alzheimer's Disease: Potential mechanisms for an association
Alzheimer's Disease (AD) and epilepsy are common neurological diseases. The prevalence
of epilepsy in AD patients is higher than in healthy subjects, but identifying the reasons for …
of epilepsy in AD patients is higher than in healthy subjects, but identifying the reasons for …
Seizures in Alzheimer's disease are highly recurrent and associated with a poor disease course
Background Seizures are an important comorbidity in Alzheimer's disease (AD). Conflicting
results regarding clinical parameters associated with seizures in AD were previously …
results regarding clinical parameters associated with seizures in AD were previously …
The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease
Y Tang, Y Yan, J Mao, J Ni, H Qing - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
Mechanisms involved in epileptogenesis in Alzheimer's disease and their therapeutic implications
Epilepsy and Alzheimer's disease (AD) incidence increases with age. There are reciprocal
relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an …
relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an …
[HTML][HTML] EEG window length evaluation for the detection of Alzheimer's disease over different brain regions
Alzheimer's Disease (AD) is a neurogenerative disorder and the most common type of
dementia with a rapidly increasing world prevalence. In this paper, the ability of several …
dementia with a rapidly increasing world prevalence. In this paper, the ability of several …
Central role for NMDA receptors in redox mediated impairment of synaptic function during aging and Alzheimer's disease
TC Foster, C Kyritsopoulos, A Kumar - Behavioural brain research, 2017 - Elsevier
Increased human longevity has magnified the negative impact that aging can have on
cognitive integrity of older individuals experiencing some decline in cognitive function …
cognitive integrity of older individuals experiencing some decline in cognitive function …
Amyloid β causes excitation/inhibition imbalance through dopamine receptor 1-dependent disruption of fast-spiking GABAergic input in anterior cingulate cortex
SQ Ren, W Yao, JZ Yan, C **, JJ Yin, J Yuan, S Yu… - Scientific reports, 2018 - nature.com
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. At the early
stages of AD development, the soluble β-amyloid (Aβ) induces synaptic dysfunction …
stages of AD development, the soluble β-amyloid (Aβ) induces synaptic dysfunction …