This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Microstructure imaging seeks to noninvasively measure and map microscopic tissue
features by pairing mathematical modeling with tailored MRI protocols. This article reviews …

This work describes a new diffusion MR framework for imaging and modeling of
microstructure that we call q-space trajectory imaging (QTI). The QTI framework consists of …

Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic
cellular parameters holds the promise of quantifying the integrity of white matter …

In diffusion MRI (dMRI), microscopic diffusion anisotropy can be obscured by orientation
dispersion. Separation of these properties is of high importance, since it could allow dMRI to …

While glia are increasingly implicated in the pathophysiology of psychiatric and
neurodegenerative disorders, available methods for imaging these cells in vivo involve …

Diffusion tensor imaging (DTI) is the method of choice for non-invasive investigations of the
structure of human brain white matter (WM). The results are conventionally reported as maps …

There is a need for biomarkers that are useful for noninvasive imaging of tumor
pathophysiology and drug efficacy. Through its use of endogenous water, diffusion-weighted …

The structural heterogeneity of tumor tissue can be probed by diffusion MRI (dMRI) in terms
of the variance of apparent diffusivities within a voxel. However, the link between the …