Nonlinear microfluidics: device physics, functions, and applications

HM **a, JW Wu, JJ Zheng, J Zhang, ZP Wang - Lab on a Chip, 2021 - pubs.rsc.org
The microfluidic flow is typically laminar due to the dominant viscous effects. At Reynolds
numbers far below 1 (Re≪ 1), the fluid inertia can be neglected. For the steady flow of …

Stiff hydrogel encapsulation retains mesenchymal stem cell stemness for regenerative medicine

B Li, L Zhang, Y Yin, A Chen, BR Seo, J Lou… - Matter, 2024 - cell.com
Mesenchymal stem cells (MSCs) stand as a prominent choice in regenerative medicine, yet
their therapeutic potential remains controversial due to challenges in maintaining lineage …

[HTML][HTML] Flow focusing with miscible fluids in microfluidic devices

G Houston, P Capobianchi, MSN Oliveira - Physics of Fluids, 2023 - pubs.aip.org
In this work, a series of experiments and numerical simulations performed using a volume-of-
fluid approach were carried out to investigate the flow of miscible viscous fluid systems …

Formation of droplet and “string of sausages” for water-ionic liquid ([BMIM][PF6]) two-phase flow in a flow-focusing device

C Liu, Q Zhang, C Zhu, T Fu, Y Ma, HZ Li - Chemical Engineering and …, 2018 - Elsevier
Dynamics of water-high-viscosity ionic liquid ([BMIM][PF 6]) two-phase flow in a flow-
focusing device were investigated by using a high-speed digital camera. Four flow regimes …

Microfluidic elongation of viscous droplets at vanishing interfacial tension

T Cubaud - Physical Review Fluids, 2023 - APS
The microflow behavior of liquid-liquid dispersions is experimentally investigated in the
presence of miscible fluid additives. Original microfluidic methods are developed to …

Droplet formation by rupture of vibration-induced interfacial fingers

SY Mak, Y Chao, S Rahman, HC Shum - Langmuir, 2018 - ACS Publications
By imposing vibration to a core-annular flow of an aqueous two-phase system (ATPS) with
ultralow interfacial tension, we observe a liquid finger protruding from the interface of an …

Viscous wave breaking and ligament formation in microfluidic systems

X Hu, T Cubaud - Physical Review Letters, 2018 - APS
Rapid layering of viscous materials in microsystems encompasses a range of hydrodynamic
instabilities that facilitate mixing and emulsification processes of fluids having large …

Deformability-and size-based microcapsule sorting

D Vesperini, O Chaput, N Munier, P Maire… - Medical Engineering & …, 2017 - Elsevier
Biomedical applications often require to sort cells according to their physical properties,
such as size, density or deformability. In recent years, microfluidics has provided a variety of …

Dynamics of high viscosity contrast confluent microfluidic flows

ME Kurdzinski, B Gol, AC Hee, P Thurgood, JY Zhu… - Scientific Reports, 2017 - nature.com
The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of
two fluids forming two stable parallel flows within a single channel meeting at a highly stable …

Pressure-driven flow focusing of two miscible liquids

I Bihi, D Vesperini, B Kaoui, A Le Goff - Physics of Fluids, 2019 - pubs.aip.org
Flow focusing consists in injecting a core liquid into another surrounding flowing sheath
liquid. Here we investigate experimentally the influence of imposing pressure to generate …