Myelofibrosis

F Passamonti, B Mora - Blood, 2023 - ashpublications.org
The clinical phenotype of primary and post–polycythemia vera and postessential
thrombocythemia myelofibrosis (MF) is dominated by splenomegaly, symptomatology, a …

Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International …

N Kröger, A Bacigalupo, T Barbui… - The Lancet …, 2024 - thelancet.com
New options for medical therapy and risk scoring systems containing molecular data are
leading to increased complexity in the management of patients with myelofibrosis. To inform …

Myeloproliferative neoplasms, version 3.2022, NCCN clinical practice guidelines in oncology

AT Gerds, J Gotlib, H Ali, P Bose, A Dunbar… - Journal of the National …, 2022 - jnccn.org
The classic Philadelphia chromosome–negative myeloproliferative neoplasms (MPN)
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …

How I treat transplant-eligible patients with myelofibrosis

N Kröger, C Wolschke, N Gagelmann - Blood, 2023 - ashpublications.org
Despite the approval of Janus kinase inhibitors and novel agents for patients with
myelofibrosis (MF), disease-modifying responses remain limited, and hematopoietic stem …

A simple prognostic system in patients with myelofibrosis undergoing allogeneic stem cell transplantation: a CIBMTR/EBMT analysis

R Tamari, DP McLornan, KW Ahn… - Blood …, 2023 - ashpublications.org
To develop a prognostic model for patients undergoing allogeneic hematopoietic cell
transplantation (allo-HCT) for myelofibrosis (MF), we examined the data of 623 patients …

Donor types and outcomes of transplantation in myelofibrosis: a CIBMTR study

T Jain, N Estrada-Merly, MQ Salas, S Kim… - Blood …, 2024 - ashpublications.org
We evaluate the impact of donor types on outcomes of hematopoietic cell transplantation
(HCT) in myelofibrosis, using the Center for International Blood and Marrow Transplant …

Graft-versus-host disease and impact on relapse in myelofibrosis undergoing hematopoietic stem cell transplantation

S Oechsler, N Gagelmann, C Wolschke… - Bone Marrow …, 2024 - nature.com
Allogeneic hematopoietic stem cell transplantation (alloHSCT) remains the only curative
treatment for myelofibrosis (MF). Relapse occurs in 10–30% and remains a major factor for …

Spleen volume and length determined by computed tomography impact outcome after allogeneic stem cell transplantation for myelofibrosis

M Luther, FO Henes, T Zabelina, R Massoud… - Bone Marrow …, 2023 - nature.com
Splenomegaly is a hallmark of myelofibrosis (MF), and reports on the impact of spleen size
on the outcome of allo-HSCT have been conflicting, possibly due to differences in methods …

The development of post-transplant cyclophosphamide: Half a century of translational team science

PV O'Donnell, RJ Jones - Blood reviews, 2023 - Elsevier
Close HLA matching of donors and recipients has been the dogma for successful allogeneic
blood or marrow transplantation (alloBMT), to limit the complications of graft-versus-host …

Post-transplantation cyclophosphamide-based graft-versus-host disease prophylaxis with nonmyeloablative conditioning for blood or marrow transplantation for …

T Jain, HL Tsai, AE DeZern, LP Gondek… - … and cellular therapy, 2022 - Elsevier
We describe outcomes after post-transplantation cyclophosphamide and nonmyeloablative
conditioning-based allogeneic blood or marrow transplantation for myelofibrosis using …