As an essential trace element, selenium (Se) plays a tremendous role in the functioning of
the human organism being used for the biosynthesis of selenoproteins (proteins containing …

Selenium is an essential micronutrient with important functions in human health and
relevance to several pathophysiological conditions. The biological effects of selenium are …

The many biological and biomedical effects of selenium are relatively unknown outside the
selenium field. This fascinating element, initially described as a toxin, was subsequently …

Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

The essential trace mineral, selenium, is of fundamental importance to human health. As a
constituent of selenoproteins, selenium has structural and enzymic roles, in the latter context …

In the genetic code, UGA serves as a stop signal and a selenocysteine codon, but no
computational methods for identifying its coding function are available. Consequently, most …

The human genome contains 25 genes coding for selenocysteine-containing proteins
(selenoproteins). These proteins are involved in a variety of functions, most notably redox …

The requirement of the trace element selenium for life and its beneficial role in human health
has been known for several decades. This is attributed to low molecular weight selenium …

Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …

The family of glutathione peroxidases comprises four distinct mammalian selenoproteins.
The classical enzyme (cGPx) is ubiquitously distributed. According to animal, cell culture …