Calcium-release channels: structure and function of IP3 receptors and ryanodine receptors
KA Woll, F Van Petegem - Physiological Reviews, 2022 - journals.physiology.org
Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …
Ischemia/reperfusion injury following acute myocardial infarction: a critical issue for clinicians and forensic pathologists
M Neri, I Riezzo, N Pascale, C Pomara… - Mediators of …, 2017 - Wiley Online Library
Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …
strategies are the current standard therapy for AMI. However, they may result in paradoxical …
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy
DG Allen, NP Whitehead… - Physiological …, 2016 - journals.physiology.org
Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …
Resistance training‐induced changes in integrated myofibrillar protein synthesis are related to hypertrophy only after attenuation of muscle damage
Key points Skeletal muscle hypertrophy is one of the main outcomes from resistance training
(RT), but how it is modulated throughout training is still unknown. We show that changes in …
(RT), but how it is modulated throughout training is still unknown. We show that changes in …
Lengthening our perspective: morphological, cellular, and molecular responses to eccentric exercise
The response of skeletal muscle to unaccustomed eccentric exercise has been studied
widely, yet it is incompletely understood. This review is intended to provide an up‐to‐date …
widely, yet it is incompletely understood. This review is intended to provide an up‐to‐date …
[HTML][HTML] Aorta-and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways
We determined whether gut microbiota-produced trimethylamine (TMA) is oxidized into
trimethylamine N-oxide (TMAO) in nonliver tissues and whether TMAO promotes …
trimethylamine N-oxide (TMAO) in nonliver tissues and whether TMAO promotes …
The role of junctophilin proteins in cellular function
Junctophilins (JPHs) comprise a family of structural proteins that connect the plasma
membrane to intracellular organelles such as the endo/sarcoplasmic reticulum (ER/SR) …
membrane to intracellular organelles such as the endo/sarcoplasmic reticulum (ER/SR) …
Insights into the molecular etiology of exercise-induced inflammation: opportunities for optimizing performance
The study of exercise-induced muscle damage (EIMD) is of paramount importance not only
because it affects athletic performance but also because it is an excellent model to study the …
because it affects athletic performance but also because it is an excellent model to study the …
[HTML][HTML] Pathophysiology of exercise-induced muscle damage and its structural, functional, metabolic, and clinical consequences
Extreme or unaccustomed eccentric exercise can cause exercise-induced muscle damage,
characterized by structural changes involving sarcomere, cytoskeletal, and membrane …
characterized by structural changes involving sarcomere, cytoskeletal, and membrane …
Skeletal and cardiac muscle calcium transport regulation in health and disease
MA Valentim, AN Brahmbhatt, AR Tupling - Bioscience Reports, 2022 - portlandpress.com
In healthy muscle, the rapid release of calcium ions (Ca2+) with excitation–contraction (EC)
coupling, results in elevations in Ca2+ concentrations which can exceed 10-fold that of …
coupling, results in elevations in Ca2+ concentrations which can exceed 10-fold that of …