Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

Candidiasis is a highly pervasive infection posing major health risks, especially for
immunocompromised populations. Pathogenic Candida species have evolved intrinsic and …

Polyploidy is a key mechanism of genome evolution and speciation, particularly in plants.
Many aspects of polyploidy have been elucidated with the tools that have become available …

Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

Polyploidization, the addition of a complete set of chromosomes to the genome, represents
one of the most dramatic mutations known to occur. Nevertheless, polyploidy is well …

Theoretical studies of adaptation have exploded over the past decade. This work has been
inspired by recent, surprising findings in the experimental study of adaptation. For example …

Fungal infections are a growing medical concern, in part due to increased resistance to one
or multiple antifungal drugs. However, the evolutionary processes underpinning the …

Resistance to the limited number of available antifungal drugs is a serious problem in the
treatment of Candida albicans. We found that aneuploidy in general and a specific …

Hsp90 is a molecular chaperone for many signal transducers and may influence evolution
by releasing previously silent genetic variation in response to environmental change. In …

Fungal pathogens exploit diverse mechanisms to survive exposure to antifungal drugs. This
poses concern given the limited number of clinically useful antifungals and the growing …