Fungal secondary metabolism: regulation, function and drug discovery

NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …

Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …

JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …

Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins

JC Frisvad, V Hubka, CN Ezekiel, SB Hong… - Studies in …, 2019 - ingentaconnect.com
Aflatoxins and ochratoxins are among the most important mycotoxins of all and producers of
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …

Sclerotinia sclerotiorum (Lib.) de Bary: Insights into the Pathogenomic Features of a Global Pathogen

MM Hossain, F Sultana, W Li, LSP Tran, MG Mostofa - Cells, 2023 - mdpi.com
Sclerotinia sclerotiorum (Lib.) de Bary is a broad host-range fungus that infects an inclusive
array of plant species and afflicts significant yield losses globally. Despite being a notorious …

[HTML][HTML] Biological valorization of low molecular weight lignin

OY Abdelaziz, DP Brink, J Prothmann, K Ravi… - Biotechnology …, 2016 - Elsevier
Lignin is a major component of lignocellulosic biomass and as such, it is processed in
enormous amounts in the pulp and paper industry worldwide. In such industry it mainly …

How a fungus shapes biotechnology: 100 years of Aspergillus niger research

TC Cairns, C Nai, V Meyer - Fungal biology and biotechnology, 2018 - Springer
In 1917, a food chemist named James Currie made a promising discovery: any strain of the
filamentous mould Aspergillus niger would produce high concentrations of citric acid when …

Fungal–fungal co-culture: a primer for generating chemical diversity

SL Knowles, HA Raja, CD Roberts… - Natural Product …, 2022 - pubs.rsc.org
Covering: 2002 to 2020 In their natural environment, fungi must compete for resources. It
has been hypothesized that this competition likely induces the biosynthesis of secondary …

Plant-polysaccharide-degrading enzymes from basidiomycetes

J Rytioja, K Hildén, J Yuzon, A Hatakka… - Microbiology and …, 2014 - Am Soc Microbiol
Basidiomycete fungi subsist on various types of plant material in diverse environments, from
living and dead trees and forest litter to crops and grasses and to decaying plant matter in …

Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery

S Bertrand, N Bohni, S Schnee, O Schumpp… - Biotechnology …, 2014 - Elsevier
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …

Genomic Analysis of the Necrotrophic Fungal Pathogens Sclerotinia sclerotiorum and Botrytis cinerea

J Amselem, CA Cuomo, JAL van Kan, M Viaud… - PLoS …, 2011 - journals.plos.org
Sclerotinia sclerotiorum and Botrytis cinerea are closely related necrotrophic plant
pathogenic fungi notable for their wide host ranges and environmental persistence. These …