Henipaviruses: epidemiology, ecology, disease, and the development of vaccines and therapeutics

JR Spengler, MK Lo, SR Welch… - Clinical Microbiology …, 2024 - journals.asm.org
Henipaviruses were first identified 30 years ago and have since been associated with over
30 outbreaks of disease in humans. Highly pathogenic henipaviruses include Hendra virus …

A systematic review on Nipah virus: global molecular epidemiology and medical countermeasures development

FH Tan, A Sukri, N Idris, KC Ong, JP Schee… - Virus …, 2024 - academic.oup.com
Nipah virus (NiV) is an emerging pathogen that causes encephalitis and a high mortality rate
in infected subjects. This systematic review aimed to comprehensively analyze the global …

Nipah virus outbreak in Kerala State, India amidst of COVID-19 pandemic

PD Yadav, RR Sahay, A Balakrishnan… - Frontiers in public …, 2022 - frontiersin.org
We report here a Nipah virus (NiV) outbreak in Kozhikode district of Kerala state, India,
which had caused fatal encephalitis in a 12-year-old boy and the outbreak response, which …

The ecology of Nipah virus in Bangladesh: a nexus of land-use change and opportunistic feeding behavior in bats

CD McKee, A Islam, SP Luby, H Salje, PJ Hudson… - Viruses, 2021 - mdpi.com
Nipah virus is a bat-borne paramyxovirus that produces yearly outbreaks of fatal
encephalitis in Bangladesh. Understanding the ecological conditions that lead to spillover …

[HTML][HTML] Rapid detection of Nipah virus using the one-pot RPA-CRISPR/Cas13a assay

J Miao, L Zuo, D He, Z Fang, N Berthet, C Yu, G Wong - Virus Research, 2023 - Elsevier
Nipah virus (NiV) is a zoonotic pathogen with airborne transmission and high case fatality
rates in humans. There is currently no treatment or vaccine against NiV infection approved …

Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman …

E de Wit, F Feldmann, J Cronin, K Goldin… - …, 2023 - thelancet.com
Summary Background Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and
neurological disease in Southeast Asia. The World Health Organization considers the …

[HTML][HTML] Optimization of Bangladesh and Malaysian genotype recombinant reporter Nipah viruses for in vitro antiviral screening and in vivo disease modeling

MK Lo, S Jain, KA Davies, TE Sorvillo, SR Welch… - Antiviral Research, 2024 - Elsevier
Nipah virus (NiV) causes near-annual outbreaks of fatal encephalitis and respiratory
disease in South Asia with a high mortality rate (∼ 70%). Since there are no approved …

Potential for person-to-person transmission of henipaviruses: A systematic review of the literature

ST Hegde, KH Lee, A Styczynski… - The Journal of …, 2024 - academic.oup.com
Abstract Nipah virus Bangladesh (NiVB) is a bat-borne zoonosis transmitted between
people through the respiratory route. The risk posed by related henipaviruses, including …

[HTML][HTML] Nipah virus detection at bat roosts after spillover events, Bangladesh, 2012–2019

CD McKee, A Islam, MZ Rahman, SU Khan… - Emerging infectious …, 2022 - ncbi.nlm.nih.gov
Abstract Knowledge of the dynamics and genetic diversity of Nipah virus circulating in bats
and at the human-animal interface is limited by current sampling efforts, which produce few …

Therapeutics for Nipah virus disease: A systematic review to support prioritisation of drug candidates for clinical trials

XHS Chan, IL Haeusler, BJK Choy, MZ Hassan… - The Lancet …, 2024 - thelancet.com
Nipah virus disease is a bat-borne zoonosis with person-to-person transmission, a case-
fatality rate of 38–75%, and well recognised potential to cause a pandemic. The first …