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[HTML][HTML] How liquid biopsies can change clinical practice in oncology
Cell-free DNA fragments are shed into the bloodstream by tumor cells. The analysis of
circulating tumor DNA (ctDNA), commonly known as liquid biopsy, can be exploited for a …
circulating tumor DNA (ctDNA), commonly known as liquid biopsy, can be exploited for a …
Toward the early detection of cancer by decoding the epigenetic and environmental fingerprints of cell-free DNA
Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …
A field guide for cancer diagnostics using cell‐free DNA: from principles to practice and clinical applications
Recently, many genome‐wide profiling studies provided insights into the molecular make‐
up of major cancer types. The deeper understanding of these genetic alterations and their …
up of major cancer types. The deeper understanding of these genetic alterations and their …
Tumor evolution as a therapeutic target
Recent technological advances in the field of molecular diagnostics (including blood-based
tumor genoty**) allow the measurement of clonal evolution in patients with cancer, thus …
tumor genoty**) allow the measurement of clonal evolution in patients with cancer, thus …
Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods
S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …
[HTML][HTML] Circulating tumor DNA—a novel biomarker of tumor progression and its favorable detection techniques
X Wen, H Pu, Q Liu, Z Guo, D Luo - Cancers, 2022 - mdpi.com
Simple Summary ctDNA is a small DNA fragment derived from tumor cells, which contains
tumor-related genomic information, such as mutation, methylation, microsatellite instability …
tumor-related genomic information, such as mutation, methylation, microsatellite instability …
Serial ctDNA monitoring to predict response to systemic therapy in metastatic gastrointestinal cancers
Purpose: ctDNA offers a promising, noninvasive approach to monitor therapeutic efficacy in
real-time. We explored whether the quantitative percent change in ctDNA early after therapy …
real-time. We explored whether the quantitative percent change in ctDNA early after therapy …
The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer
M Reece, H Saluja, P Hollington, CS Karapetis… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a
high mortality rate following disease recurrence. Treatment efficacy is maximized by …
high mortality rate following disease recurrence. Treatment efficacy is maximized by …
[HTML][HTML] How to use liquid biopsies to treat patients with cancer
L De Mattos-Arruda, G Siravegna - ESMO open, 2021 - Elsevier
Precision medicine is now pivotal to design patients' specific treatment strategies with the
aim of prolonging progression and overall survival. In this regard, invasive tumor tissue …
aim of prolonging progression and overall survival. In this regard, invasive tumor tissue …
Clinical applications of urinary cell-free DNA in cancer: current insights and promising future
T Lu, J Li - American journal of cancer research, 2017 - pmc.ncbi.nlm.nih.gov
Liquid biopsy is gaining significant attention as a tool for unveiling the molecular landscape
of tumor and holds great promise for individualized medicine for cancer. Cell-free DNA …
of tumor and holds great promise for individualized medicine for cancer. Cell-free DNA …