[HTML][HTML] How liquid biopsies can change clinical practice in oncology

G Siravegna, B Mussolin, T Venesio, S Marsoni… - Annals of …, 2019 - Elsevier
Cell-free DNA fragments are shed into the bloodstream by tumor cells. The analysis of
circulating tumor DNA (ctDNA), commonly known as liquid biopsy, can be exploited for a …

Toward the early detection of cancer by decoding the epigenetic and environmental fingerprints of cell-free DNA

Y Van Der Pol, F Mouliere - Cancer cell, 2019 - cell.com
Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …

A field guide for cancer diagnostics using cell‐free DNA: from principles to practice and clinical applications

AL Volckmar, H Sültmann, A Riediger… - Genes …, 2018 - Wiley Online Library
Recently, many genome‐wide profiling studies provided insights into the molecular make‐
up of major cancer types. The deeper understanding of these genetic alterations and their …

Tumor evolution as a therapeutic target

N Amirouchene-Angelozzi, C Swanton… - Cancer discovery, 2017 - aacrjournals.org
Recent technological advances in the field of molecular diagnostics (including blood-based
tumor genoty**) allow the measurement of clonal evolution in patients with cancer, thus …

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

[HTML][HTML] Circulating tumor DNA—a novel biomarker of tumor progression and its favorable detection techniques

X Wen, H Pu, Q Liu, Z Guo, D Luo - Cancers, 2022 - mdpi.com
Simple Summary ctDNA is a small DNA fragment derived from tumor cells, which contains
tumor-related genomic information, such as mutation, methylation, microsatellite instability …

Serial ctDNA monitoring to predict response to systemic therapy in metastatic gastrointestinal cancers

AR Parikh, A Mojtahed, JL Schneider… - Clinical Cancer …, 2020 - aacrjournals.org
Purpose: ctDNA offers a promising, noninvasive approach to monitor therapeutic efficacy in
real-time. We explored whether the quantitative percent change in ctDNA early after therapy …

The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer

M Reece, H Saluja, P Hollington, CS Karapetis… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a
high mortality rate following disease recurrence. Treatment efficacy is maximized by …

[HTML][HTML] How to use liquid biopsies to treat patients with cancer

L De Mattos-Arruda, G Siravegna - ESMO open, 2021 - Elsevier
Precision medicine is now pivotal to design patients' specific treatment strategies with the
aim of prolonging progression and overall survival. In this regard, invasive tumor tissue …

Clinical applications of urinary cell-free DNA in cancer: current insights and promising future

T Lu, J Li - American journal of cancer research, 2017 - pmc.ncbi.nlm.nih.gov
Liquid biopsy is gaining significant attention as a tool for unveiling the molecular landscape
of tumor and holds great promise for individualized medicine for cancer. Cell-free DNA …