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Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …
key observation is the disruption of cellular homeostasis, often coinciding with disease …
Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …
spread of genes coding for resistance determinants among bacteria challenges the use of …
DNAzyme‐loaded metal–organic frameworks (MOFs) for self‐sufficient gene therapy
DNAzymes have been recognized as potent therapeutic agents for gene therapy, while their
inefficient intracellular delivery and insufficient cofactor supply precludes their practical …
inefficient intracellular delivery and insufficient cofactor supply precludes their practical …
Metal homeostasis and resistance in bacteria
Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria,
metal limitation activates pathways that are involved in the import and mobilization of metals …
metal limitation activates pathways that are involved in the import and mobilization of metals …
Decoding catalysis by terpene synthases
The review by Christianson, published in 2017 on the twentieth anniversary of the
emergence of the field, summarizes the foundational discoveries and key advances in …
emergence of the field, summarizes the foundational discoveries and key advances in …
[PDF][PDF] Role of zinc nutrition for increasing zinc availability, uptake, yield, and quality of maize (Zea mays L.) grains: An overview
A Suganya, A Saravanan… - Commun. Soil Sci. Plant …, 2020 - researchgate.net
Maize (Zea mays L.) is one of the most versatile crops and can be grown in diverse
environmental conditions and has diversified uses as human food and animal feed. Maize …
environmental conditions and has diversified uses as human food and animal feed. Maize …
The role of oxidative stress and hypoxia in pancreatic beta-cell dysfunction in diabetes mellitus
Significance: Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a
disease that currently affects∼ 8% of the adult population worldwide. Pancreatic beta-cell …
disease that currently affects∼ 8% of the adult population worldwide. Pancreatic beta-cell …
Zinc transporters and their functional integration in mammalian cells
Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …
[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism
T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
[HTML][HTML] Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis
T Hara, T Takeda, T Takagishi, K Fukue… - The Journal of …, 2017 - Elsevier
Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …