Non-viral vectors in gene therapy: recent development, challenges, and prospects
H Zu, D Gao - The AAPS journal, 2021 - Springer
Gene therapy has been experiencing a breakthrough in recent years, targeting various
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …
Biopolymers based aerogels: A review on revolutionary solutions for smart therapeutics delivery
Biopolymers-based aerogels have gained the attention of many scientists in medical and
pharmaceutical applications. Biopolymers-based aerogels are utilized extensively in the …
pharmaceutical applications. Biopolymers-based aerogels are utilized extensively in the …
[HTML][HTML] Polyethylenimine (PEI) in gene therapy: Current status and clinical applications
J Casper, SH Schenk, E Parhizkar, P Detampel… - Journal of Controlled …, 2023 - Elsevier
Polyethlyenimine (PEI) was introduced 1995 as a cationic polymer for nucleic acid delivery.
PEI and its derivatives are extensively used in basic research and as reference formulations …
PEI and its derivatives are extensively used in basic research and as reference formulations …
Cationic polysaccharide conjugates as antibiotic adjuvants resensitize multidrug‐resistant bacteria and prevent resistance
S Mu, Y Zhu, Y Wang, S Qu, Y Huang… - Advanced …, 2022 - Wiley Online Library
In recent years, traditional antibiotic efficacy has rapidly diminished due to the advent of
multidrug‐resistant (MDR) bacteria, which poses severe threat to human life and globalized …
multidrug‐resistant (MDR) bacteria, which poses severe threat to human life and globalized …
[HTML][HTML] Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic
Gene therapy using nucleic acids has many clinical applications for the treatment of
diseases with a genetic origin as well as for the development of innovative vaccine …
diseases with a genetic origin as well as for the development of innovative vaccine …
Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy
W **a, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …
receive chemotherapy and radiotherapy, but these treatments are usually only partially …
Degradable polymeric bio (nano) materials and their biomedical applications: A comprehensive overview and recent updates
Degradable polymers (both biomacromolecules and several synthetic polymers) for
biomedical applications have been promising very much in the recent past due to their low …
biomedical applications have been promising very much in the recent past due to their low …
[HTML][HTML] Biodegradable polymeric nanoparticle-based drug delivery systems: comprehensive overview, perspectives and challenges
M Geszke-Moritz, M Moritz - Polymers, 2024 - mdpi.com
In the last few decades, there has been a growing interest in the use of biodegradable
polymeric nanoparticles (BPNPs) as the carriers for various therapeutic agents in drug …
polymeric nanoparticles (BPNPs) as the carriers for various therapeutic agents in drug …
Current-status and applications of polysaccharides in drug delivery systems
The polysaccharide-based advanced drug delivery system owing to their biocompatibility,
ability to encapsulate the drug molecules in their interspaces, and ability to achieve a …
ability to encapsulate the drug molecules in their interspaces, and ability to achieve a …
Amino acid derived biopolymers: Recent advances and biomedical applications
Over the past few years, amino acids (AA) have emerged as promising biomaterials for the
synthesis of functional polymers. Owing to the diversity of functional groups in amino acids …
synthesis of functional polymers. Owing to the diversity of functional groups in amino acids …