Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

[HTML][HTML] A new family of constitutive artificial neural networks towards automated model discovery

K Linka, E Kuhl - Computer Methods in Applied Mechanics and …, 2023 - Elsevier
For more than 100 years, chemical, physical, and material scientists have proposed
competing constitutive models to best characterize the behavior of natural and man-made …

Hyperelastic structures: A review on the mechanics and biomechanics

HB Khaniki, MH Ghayesh, R Chin, M Amabili - International Journal of Non …, 2023 - Elsevier
Soft structures are capable of undergoing reversible large strains and deformations when
facing different types of loadings. Due to the limitations of linear elastic models, researchers …

[HTML][HTML] Mechanics in the nervous system: from development to disease

EK Pillai, K Franze - Neuron, 2024 - cell.com
Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Tissue mimicking materials for imaging and therapy phantoms: a review

CK McGarry, LJ Grattan, AM Ivory, F Leek… - Physics in Medicine …, 2020 - iopscience.iop.org
Tissue mimicking materials (TMMs), typically contained within phantoms, have been used
for many decades in both imaging and therapeutic applications. This review investigates the …

[HTML][HTML] I too I2: A new class of hyperelastic isotropic incompressible models based solely on the second invariant

E Kuhl, A Goriely - Journal of the Mechanics and Physics of Solids, 2024 - Elsevier
In contemporary elasticity theory, the strain–energy function predominantly relies on the first
invariant I 1 of the deformation tensor; a practice that has been influenced by models derived …

The soft mechanical signature of glial scars in the central nervous system

E Moeendarbary, IP Weber, GK Sheridan… - Nature …, 2017 - nature.com
Injury to the central nervous system (CNS) alters the molecular and cellular composition of
neural tissue and leads to glial scarring, which inhibits the regrowth of damaged axons …

Automated model discovery for human brain using constitutive artificial neural networks

K Linka, SRS Pierre, E Kuhl - Acta Biomaterialia, 2023 - Elsevier
The brain is our softest and most vulnerable organ, and understanding its physics is a
challenging but significant task. Throughout the past decade, numerous competing models …

A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke

Z Lyu, J Park, KM Kim, HJ **, H Wu… - Nature biomedical …, 2021 - nature.com
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …