Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

An elevated bone microenvironmental reactive oxygen species (ROS) level is a hallmark of
osteoporosis that often leads to the dysfunction of bone-related mesenchymal stem cells …

The complex relationship between mitochondrial dynamics and autophagy illustrates how
two cellular housekee** processes are intimately linked, illuminating fundamental …

Lipid–protein interactions in cells are involved in various biological processes, including
metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane …

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …

Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …

Cardiolipin (CL) is a mitochondria-exclusive phospholipid synthesized in the inner
mitochondrial membrane. CL plays a key role in mitochondrial membranes, impacting a …

Mitochondria, which generate ATP through aerobic respiration, also have important
noncanonical functions. Mitochondria are dynamic organelles, that engage in fission …

Division of intracellular organelles often correlates with additional membrane wrap**, eg,
by the endoplasmic reticulum or the outer mitochondrial membrane. Such wrap** plays a …