Bacteriophage infection, a pivotal process in microbiology, initiates with the phage's tail
recognizing and binding to the bacterial cell surface, which then mediates the injection of …

Interactions between species catalyze the evolution of multiscale ecological networks,
including both nested and modular elements that regulate the function of diverse …

Symbiosis, the living together of unlike organisms as symbionts, is ubiquitous in the natural
world. Symbioses occur within and across all scales of life, from microbial to macro-faunal …

Predicting how new mutations alter phenotypes is difficult because mutational effects vary
across genotypes and environments. Recently discovered global epistasis, in which the …

Bacteriophages have received recent attention for their therapeutic potential to treat
antibiotic-resistant bacterial infections. One particular idea in phage therapy is to use …

Predicting the evolution of virus host range has proven to be extremely difficult, in part
because of the sheer diversity of viruses, each with unique biology and ecological …

Phage therapy is a promising method for the treatment of multidrug-resistant bacterial
infections. However, its long-term efficacy depends on understanding the evolutionary …

The evolution and spread of antibiotic‐resistant bacteria have renewed interest in phage
therapy, the use of bacterial viruses (phages) to combat bacterial infections. The delivery of …

A major challenge in evolutionary biology is explaining how populations navigate rugged
fitness landscapes without getting trapped on local optima. One idea illustrated by adaptive …

Viruses that infect bacteria, known as bacteriophages or phages, are the most prevalent
entities on Earth. Their genetic diversity in nature is well documented, and members of …