Chemistry of α-oxoesters: a powerful tool for the synthesis of heterocycles

B Eftekhari-Sis, M Zirak - Chemical reviews, 2015 - ACS Publications
Heterocycles are an important class of organic compounds accounting for nearly one-third of
the past decade's publications, which are in the field of heterocyclic chemistry. In fact, two …

Quinoxalines, Volume 61, Spplement 2

DJ Brown, EC Taylor, JA Ellman - 2004 - books.google.com
This volume in the Chemistry of Heterocyclic Compounds series presents a comprehensive
review of the quinoxaline literature from 1975 to the present (2002), updating Volumes 5 and …

Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives

OO Ajani, CA Obafemi, OC Nwinyi… - Bioorganic & medicinal …, 2010 - Elsevier
A simple and efficient method has been developed for the synthesis of various 2-
quinoxalinone-3-hydrazone derivatives using microwave irradiation technique. The series of …

Synthesis of certain substituted quinoxalines as antimicrobial agents (part II)

MM Badran, KAM Abouzid, MHM Hussein - Archives of pharmacal …, 2003 - Springer
Several fused triazolo and ditriazoloquinoxaline derivatives such as 1-aryl-4-chloro-[1, 2, 4]
triazolo [4, 3-a] quinoxalines (3a-d), 4-alkoxy [1, 2, 4] triazolo [4, 3-a] quinoxalines (4a, b), 4 …

Synthesis and biological evaluation of some novel thiazole substituted benzotriazole derivatives

ND Gaikwad, SV Patil, VD Bobade - Bioorganic & medicinal chemistry …, 2012 - Elsevier
A series of novel hybrid molecules 4a–y containing thiazole and benzotriazole templates
were designed and synthesized. The structures of the synthesized compounds were …

Microwave assisted synthesis and structure–activity relationship of 4-hydroxy-N′-[1-phenylethylidene]-2H/2-methyl-1, 2-benzothiazine-3-carbohydrazide 1, 1 …

N Ahmad, M Zia-ur-Rehman, HL Siddiqui… - European journal of …, 2011 - Elsevier
A series of 4-hydroxy-N′-[1-phenylethylidene]-2H/2-methyl, 1, 2-benzothiazine-3-
carbohydrazide 1, 1-dioxides was synthesized from commercially available sodium …

Synthesis, monoamine oxidase inhibition activity and molecular docking studies of novel 4-hydroxy-N′-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl-1, 2 …

FA Saddique, S Zaib, S Jalil, S Aslam, M Ahmad… - European journal of …, 2018 - Elsevier
Three series of 4-hydroxy-N′-[benzylidene/1-phenylethylidene]-2-H/methyl/benzyl-1, 2-
benzothiazine-3-carbohydrazide 1, 1-dioxides (9–11) al were synthesized and unraveled to …

Design, synthesis and photoinduced DNA cleavage studies of [1, 2, 4]-triazolo [4, 3-a] quinoxalin-4 (5H)-ones

G Sumran, R Aggarwal, A Mittal, A Aggarwal… - Bioorganic …, 2019 - Elsevier
An expedient and eco-friendly synthesis of 1-aryl/heteroaryl-[1, 2, 4]-triazolo [4, 3-a]
quinoxalin-4 (5H)-ones (4) has been accomplished via iodobenzene diacetate mediated …

Synthesis of [1, 2, 4] triazolo [4, 3-α] piperazines via highly reactive chloromethyloxadiazoles

J Balsells, L DiMichele, J Liu, M Kubryk, K Hansen… - Organic …, 2005 - ACS Publications
A concise, modular approach for the synthesis of [1, 2, 4] triazolo [4, 3-α] piperazines via
condensation of highly reactive chloromethyloxadiazoles with ethylenediamines is …

New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase

FAS Alasmary, FS Alnahdi, A Ben Bacha… - Journal of enzyme …, 2017 - Taylor & Francis
Elevated blood glucose and increased activities of secreted phospholipase A2 (sPLA2) are
strongly linked to coronary heart disease. In this report, our goal was to develop small …