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Development and functional diversification of cortical interneurons
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …
collection of cell types that are characterized by their unique spatial and temporal …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
[HTML][HTML] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …
or genetic attributes. To better constrain the definition of neuronal cell types, we …
Conserved cell types with divergent features in human versus mouse cortex
Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …
Innovations present in the primate interneuron repertoire
Primates and rodents, which descended from a common ancestor around 90 million years
ago, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for …
ago, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for …
Shared and distinct transcriptomic cell types across neocortical areas
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …
functionally distinct areas. To investigate the diversity of cell types across the mouse …
A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality
Modern genetic approaches are powerful in providing access to diverse cell types in the
brain and facilitating the study of their function. Here, we report a large set of driver and …
brain and facilitating the study of their function. Here, we report a large set of driver and …
[HTML][HTML] Cortical somatostatin interneuron subtypes form cell-type-specific circuits
The cardinal classes are a useful simplification of cortical interneuron diversity, but such
broad subgrou**s gloss over the molecular, morphological, and circuit specificity of …
broad subgrou**s gloss over the molecular, morphological, and circuit specificity of …
Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However …
millisecond-scale interactions among and between targeted cell populations. However …