Mesoporous, degradable hyaluronic acid microparticles for sustainable drug delivery application
Porous and degradable hyaluronic acid (HA) microparticles was synthesized in a single step
using different ratio of crosslinker, divinylsulfone (DVS) ranging between 2.5 and 100% mole …
using different ratio of crosslinker, divinylsulfone (DVS) ranging between 2.5 and 100% mole …
PEGAylated graphene oxide/superparamagnetic nanocomposite as a high-efficiency loading nanocarrier for controlled delivery of methotrexate
Polymer-coated nanocarriers play an important role in targeted drug delivery. The use of
polymers such as polyethylene glycol increases stability, biocompatibility, and blood …
polymers such as polyethylene glycol increases stability, biocompatibility, and blood …
The pH-Dependent Controlled Release of Encapsulated Vitamin B1 from Liposomal Nanocarrier
In this work, we firstly presented a simple encapsulation method to prepare thiamine
hydrochloride (vitamin B1)-loaded asolectin-based liposomes with average hydrodynamic …
hydrochloride (vitamin B1)-loaded asolectin-based liposomes with average hydrodynamic …
Porous Silicon Microparticles Enable Sustained Release of GLP‐1R Agonist Peptides for the Treatment of Type 2 Diabetes
GLP‐1R agonist peptides play a prominent role in the treatment of type 2 diabetes.
However, these peptides often suffer from short plasma half‐life, rapid clearance, and low in …
However, these peptides often suffer from short plasma half‐life, rapid clearance, and low in …
[HTML][HTML] Folic acid-mesoporous silicon nanoparticles enhance the anticancer activity of the p73-activating small molecule LEM2
AS Gomes, A Correia, A Rahikkala, E Mäkilä… - International Journal of …, 2022 - Elsevier
Many drugs with anticancer potential fail in their translation to the clinics due to problems
related to pharmacokinetics. LEM2 is a new dual inhibitor of MDM2/mutp53-TAp73 …
related to pharmacokinetics. LEM2 is a new dual inhibitor of MDM2/mutp53-TAp73 …
Biogenic nanoporous silicon carrier improves the efficacy of buparvaquone against resistant visceral leishmaniasis
R Thapa, S Mondal, J Riikonen… - PLoS Neglected …, 2021 - journals.plos.org
Visceral leishmaniasis is a vector-borne protozoan infection that is fatal if untreated. There is
no vaccination against the disease, and the current chemotherapeutic agents are ineffective …
no vaccination against the disease, and the current chemotherapeutic agents are ineffective …
Surface modified porous silicon with chitosan coating as a pH-responsive controlled delivery system for lutein
W Li, D Liu, L Song, H Li, S Dai, Y Su, Q Li, J Li… - Food & Function, 2022 - pubs.rsc.org
Surface modified pH-responsive porous silicon (PSi) carriers were developed for efficient
delivery of lutein. PSi particles were prepared by the electrochemical etching method and …
delivery of lutein. PSi particles were prepared by the electrochemical etching method and …
Site-Specific 111In-Radiolabeling of Dual-PEGylated Porous Silicon Nanoparticles and Their In Vivo Evaluation in Murine 4T1 Breast Cancer Model
D Lumen, S Näkki, S Imlimthan, E Lambidis… - Pharmaceutics, 2019 - mdpi.com
Polyethylene glycol (PEG) has been successfully used for improving circulation time of
several nanomaterials but prolonging the circulation of porous silicon nanoparticles (PSi …
several nanomaterials but prolonging the circulation of porous silicon nanoparticles (PSi …
Inorganic mesoporous particles for controlled α-linolenic acid delivery to stimulate GLP-1 secretion in vitro
Novel treatment methods for obesity are urgently needed due to the increasing global
severity of the problem. Gastrointestinal hormones, such as GLP-1 and PYY, are secreted by …
severity of the problem. Gastrointestinal hormones, such as GLP-1 and PYY, are secreted by …
Principles of regulating particle multiscale structures for controlling particle-cell interaction process
C Song, X Zhang, W Wei, G Ma - Chemical Engineering Science, 2021 - Elsevier
Particles make extensively physical contact with cells after entering the body, which mediate
a series of particle-cell interaction processes. These interaction processes induce different …
a series of particle-cell interaction processes. These interaction processes induce different …