Drug delivery systems, CNS protection, and the blood brain barrier

RK Upadhyay - BioMed research international, 2014 - Wiley Online Library
Present review highlights various drug delivery systems used for delivery of pharmaceutical
agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic …

Transmission electron microscopy as a powerful tool to investigate the interaction of nanoparticles with subcellular structures

M Malatesta - International Journal of Molecular Sciences, 2021 - mdpi.com
Nanomedical research necessarily involves the study of the interactions between
nanoparticulates and the biological environment. Transmission electron microscopy has …

Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes

X Li, Y Wang, L Shi, B Li, J Li, Z Wei, H Lv, L Wu… - Journal of …, 2020 - Springer
Human mesenchymal stem cell (MSC)-derived exosomes (Exos) are a promising
therapeutic agent for cell-free regenerative medicine. However, their poor organ-targeting …

Microscopy based methods for characterization, drug delivery, and understanding the dynamics of nanoparticles

P Gupta, N Rai, A Verma… - Medicinal Research …, 2024 - Wiley Online Library
Nanomedicine is an emerging field that exploits nanotechnology for the development of
novel therapeutic and diagnostic modalities. Researches are been focussed in nanoimaging …

Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes

A Busato, R Bonafede, P Bontempi… - International journal …, 2016 - Taylor & Francis
Purpose Recent findings indicate that the beneficial effects of adipose stem cells (ASCs),
reported in several neurodegenerative experimental models, could be due to their paracrine …

Nanoparticles for brain-specific drug and genetic material delivery, imaging and diagnosis

I Posadas, S Monteagudo, V Cena - Nanomedicine, 2016 - Taylor & Francis
The poor access of therapeutic drugs and genetic material into the central nervous system
due to the presence of the blood–brain barrier often limits the development of effective …

[HTML][HTML] In vitro development of controlled-release nanoniosomes for improved delivery and anticancer activity of letrozole for breast cancer treatment

S Ahmadi, M Seraj, M Chiani, S Hosseini… - International Journal …, 2022 - ncbi.nlm.nih.gov
Materials and Methods Various niosomal formulations of letrozole were fabricated through
thin-film hydration method and characterized in terms of size, polydispersity index (PDI) …

Uptake and Intracellular Fate of Engineered Nanoparticles in Mammalian Cells: Capabilities and Limitations of Transmission Electron Microscopy—Polymer‐Based …

M Reifarth, S Hoeppener, US Schubert - Advanced Materials, 2018 - Wiley Online Library
In order to elucidate mechanisms of nanoparticle (NP)–cell interactions, a detailed
knowledge about membrane–particle interactions, intracellular distributions, and nucleus …

Niosomal delivery of simvastatin to MDA-MB-231 cancer cells

I Akbarzadeh, A Saremi Poor, S Yaghmaei… - Drug Development …, 2020 - Taylor & Francis
Objective The objective of this study was to use nano-niosomal formulations to deliver
simvastatin as a poor-water soluble drug into breast cancer cells. Significance Our study …

Singlet oxygen-based photoelectrochemical detection of DNA

ST Shanmugam, S Trashin, K De Wael - Biosensors and Bioelectronics, 2022 - Elsevier
The current work, designed for the photoelectrochemical detection of DNA, evaluates light-
responsive DNA probes carrying molecular photosensitizers generating singlet oxygen (1 O …