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The role of platelets in immune-mediated inflammatory diseases
M Scherlinger, C Richez, GC Tsokos… - Nature Reviews …, 2023 - nature.com
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
Neutrophils in chronic inflammatory diseases
A Herrero-Cervera, O Soehnlein… - Cellular & molecular …, 2022 - nature.com
Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours
Q Wang, Q Liang, J Dou, H Zhou, C Zeng, H Pan… - Nature …, 2024 - nature.com
An effective nanotherapeutic transport from the vasculature to the tumour is crucial for
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …
Interplay between inflammation and thrombosis in cardiovascular pathology
K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies
A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …
Despite significant advances in recanalization strategies, patients are still at risk for …
Immune pathways in etiology, acute phase, and chronic sequelae of ischemic stroke
Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …
development, acute damage cascades, and chronic course after ischemic stroke …
Targeting potential drivers of COVID-19: Neutrophil extracellular traps
BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Coronavirus disease 2019 (COVID-19) is a novel, viral-induced respiratory disease that in∼
10–15% of patients progresses to acute respiratory distress syndrome (ARDS) triggered by …
10–15% of patients progresses to acute respiratory distress syndrome (ARDS) triggered by …
Immunothrombotic dysregulation in COVID-19 pneumonia is associated with respiratory failure and coagulopathy
Background: Severe acute respiratory syndrome corona virus 2 infection causes severe
pneumonia (coronavirus disease 2019 [COVID-19]), but the mechanisms of subsequent …
pneumonia (coronavirus disease 2019 [COVID-19]), but the mechanisms of subsequent …
Neutrophils in COVID-19
N Reusch, E De Domenico, L Bonaguro… - Frontiers in …, 2021 - frontiersin.org
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …
neutrophils play an important role in the pathophysiology, particularly in those with severe …
Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …