Transcription factors (TFs) recognize specific DNA sequences to control chromatin and
transcription, forming a complex system that guides expression of the genome. Despite keen …

The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …

Abstract SMART (Simple Modular Architecture Research Tool) is a web resource
(http://smart. embl. de) for the identification and annotation of protein domains and the …

N 6-methyladenosine (m6A) is the most abundant internal modification of eukaryotic
messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this …

Abstract NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular
sequences with the location of evolutionarily conserved protein domain footprints, and …

Abstract InterPro (http://www. ebi. ac. uk/interpro/) is a freely available database used to
classify protein sequences into families and to predict the presence of important domains …

The origin and cellular complexity of eukaryotes represent a major enigma in biology.
Current data support scenarios in which an archaeal host cell and an alphaproteobacterial …

In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding proteins into stress
granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels …

Objectives Plasmid-mediated mobilized colistin resistance is currently known to be caused
by phosphoethanolamine transferases termed MCR-1, MCR-2, MCR-3 and MCR-4 …

Abstract eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at
different taxonomic levels, each with integrated and summarized functional annotations …