[HTML][HTML] Stem cell therapy for Alzheimer's disease

XY Liu, LP Yang, L Zhao - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …

Neurogenesis and inflammation after ischemic stroke: what is known and where we go from here

MK Tobin, JA Bonds, RD Minshall… - Journal of Cerebral …, 2014 - journals.sagepub.com
This review covers the pathogenesis of ischemic stroke and future directions regarding
therapeutic options after injury. Ischemic stroke is a devastating disease process affecting …

Factors that influence adult neurogenesis as potential therapy

B Shohayeb, M Diab, M Ahmed, DCH Ng - Translational …, 2018 - Springer
Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …

When neurogenesis encounters aging and disease

O Lazarov, MP Mattson, DA Peterson… - Trends in …, 2010 - cell.com
In this review, we consider the evidence that a reduction in neurogenesis underlies aging-
related cognitive deficits and impairments in disorders such as Alzheimer's disease (AD) …

Physical exercise induces hippocampal neurogenesis and prevents cognitive decline

CL Ma, XT Ma, JJ Wang, H Liu, YF Chen… - Behavioural brain …, 2017 - Elsevier
Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …

Disruption of neurogenesis by amyloid β‐peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

NJ Haughey, A Nath, SL Chan… - Journal of …, 2002 - Wiley Online Library
Neurogenesis occurs in the adult mammalian brain and may play roles in learning and
memory processes and recovery from injury, suggesting that abnormalities in neural …

Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia

K Chu, M Kim, KI Park, SW Jeong, HK Park, KH Jung… - Brain research, 2004 - Elsevier
Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain
damage with long-term sensorimotor deficits. Stem cell transplantation may recover …

Stem cell therapies for neurodegenerative diseases

K Sugaya, M Vaidya - Exosomes, stem cells and MicroRNA: aging, cancer …, 2018 - Springer
Stem cell therapies have been proposed as a treatment option for neurodegenerative
diseases, but the best stem cell source and therapeutic efficacy for neuroregeneration …

[HTML][HTML] Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions

E Nivet, M Vignes, SD Girard… - The Journal of …, 2011 - Am Soc Clin Investig
Stem cell–based therapy has been proposed as a potential means of treatment for a variety
of brain disorders. Because ethical and technical issues have so far limited the clinical …

Adult hippocampal neurogenesis in Alzheimer's disease: an overview of human and animal studies with implications for therapeutic perspectives aimed at memory …

S Farioli-Vecchioli, V Ricci, S Middei - Neural Plasticity, 2022 - Wiley Online Library
The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural
stem cells. Newborn neurons integrate into existing neuronal networks, where they play a …