Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
DNA nanotechnology-enabled drug delivery systems
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
P-selectin-targeted nanocarriers induce active crossing of the blood–brain barrier via caveolin-1-dependent transcytosis
DE Tylawsky, H Kiguchi, J Vaynshteyn, J Gerwin… - Nature materials, 2023 - nature.com
Medulloblastoma is the most common malignant paediatric brain tumour, with~ 30%
mediated by Sonic hedgehog signalling. Vismodegib-mediated inhibition of the Sonic …
mediated by Sonic hedgehog signalling. Vismodegib-mediated inhibition of the Sonic …
The entry of nanoparticles into solid tumours
The concept of nanoparticle transport through gaps between endothelial cells (inter-
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …
Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
Magnetic nanoparticles in targeted drug delivery: a review
E Kianfar - Journal of Superconductivity and Novel Magnetism, 2021 - Springer
Magnetic nanoparticles are one of the most important and widely used types of
nanomaterials, whose unique properties make them special compared to other …
nanomaterials, whose unique properties make them special compared to other …
Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery
To accelerate the translation of cancer nanomedicine, we used an integrated genomic
approach to improve our understanding of the cellular processes that govern nanoparticle …
approach to improve our understanding of the cellular processes that govern nanoparticle …
Effect of the surface modification, size, and shape on cellular uptake of nanoparticles
Nowadays successful application of nanoparticles for therapeutic objects needs the effective
uptake of them by cells. Hence, studying of the interaction of nanoparticles with cell …
uptake of them by cells. Hence, studying of the interaction of nanoparticles with cell …
Surface-engineered dendrimers in gene delivery
J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …
produced and used in many commercial products, which could lead to the contact of human …