Zebrafish larvae as a behavioral model in neuropharmacology

RM Basnet, D Zizioli, S Taweedet, D Finazzi, M Memo - Biomedicines, 2019 - mdpi.com
Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …

Zebrafish as an emerging model for studying complex brain disorders

AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

Zebrafish models for translational neuroscience research: from tank to bedside

AM Stewart, O Braubach, J Spitsbergen, R Gerlai… - Trends in …, 2014 - cell.com
The zebrafish (Danio rerio) is emerging as a new important species for studying
mechanisms of brain function and dysfunction. Focusing on selected central nervous system …

Exposure to microplastics decreases swimming competence in larval zebrafish (Danio rerio)

L Qiang, J Cheng - Ecotoxicology and environmental safety, 2019 - Elsevier
Microplastics have been frequently detected in both marine and freshwater ecosystems.
Their impact on aquatic organisms has raised much concern. This study investigated the …

Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy

I Javed, G Peng, Y **ng, T Yu, M Zhao… - Nature …, 2019 - nature.com
Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disorders, yet no
major breakthroughs have been made in AD human trials and the disease remains a …

Measuring thigmotaxis in larval zebrafish

SJ Schnörr, PJ Steenbergen, MK Richardson… - Behavioural brain …, 2012 - Elsevier
One of the most commonly used behavioral endpoints measured in preclinical studies using
rodent models is thigmotaxis (or “wall-hugging”). Thigmotaxis is a well-validated index of …

Modeling anxiety using adult zebrafish: a conceptual review

A Stewart, S Gaikwad, E Kyzar, J Green, A Roth… - …, 2012 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as a useful animal model in neurobehavioral
research. Mounting evidence shows the suitability of zebrafish to model various aspects of …

Comparative analyses of zebrafish anxiety-like behavior using conflict-based novelty tests

EV Kysil, DA Meshalkina, EE Frick, DJ Echevarria… - Zebrafish, 2017 - liebertpub.com
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in
neuroscience research and central nervous system (CNS) drug discovery. Representing the …

Gaining translational momentum: more zebrafish models for neuroscience research

AV Kalueff, DJ Echevarria, AM Stewart - Progress in Neuro …, 2014 - Elsevier
Zebrafish (Danio rerio) are rapidly becoming a popular model organism in translational
neuroscience and biological psychiatry research. Here we discuss conceptual, practical and …

Molecular psychiatry of zebrafish

AM Stewart, JFP Ullmann, WHJ Norton, MO Parker… - Molecular …, 2015 - nature.com
Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …