Trends in big data analyses by multicenter collaborative translational research in psychiatry

T Onitsuka, Y Hirano, K Nemoto… - Psychiatry and …, 2022 - Wiley Online Library
The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …

Selective review of neuroimaging findings in youth at clinical high risk for psychosis: on the path to biomarkers for conversion

JK Ellis, EF Walker, DR Goldsmith - Frontiers in Psychiatry, 2020 - frontiersin.org
First episode psychosis (FEP), and subsequent diagnosis of schizophrenia or
schizoaffective disorder, predominantly occurs during late adolescence, is accompanied by …

Distinct volume alterations of thalamic nuclei across the schizophrenia spectrum

M Thalhammer, J Schulz, F Scheulen… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis Abnormal thalamic nuclei volumes and their link to
cognitive impairments have been observed in schizophrenia. However, whether and how …

Identifying common and distinct subcortical volumetric abnormalities in 3 major psychiatric disorders: a single-site analysis of 640 participants

PC Tu, WC Chang, MH Chen, JW Hsu, WC Lin… - Journal of Psychiatry and …, 2022 - jpn.ca
Background Subcortical volumetric abnormalities in schizophrenia, bipolar disorder and
major depressive disorder (MDD) have been consistently found on a single-diagnosis basis …

Reduced hippocampal subfield volume in schizophrenia and clinical high-risk state for psychosis

D Sasabayashi, R Yoshimura, T Takahashi… - Frontiers in …, 2021 - frontiersin.org
Magnetic resonance imaging (MRI) studies in schizophrenia demonstrated volume
reduction in hippocampal subfields divided on the basis of specific cytoarchitecture and …

A subtype of institutionalized patients with schizophrenia characterized by pronounced subcortical and cognitive deficits

Q Zhao, H Cao, W Zhang, S Li, Y **ao… - …, 2022 - nature.com
Some patients with schizophrenia have severe cognitive impairment and functional deficits
that require long-term institutional care. The patterns of brain-behavior alterations in these …

Reduced GABA/glutamate in the thalamus of individuals at clinical high risk for psychosis

GM Quiñones, A Mayeli, VE Yushmanov… - …, 2021 - nature.com
Youth at clinical high risk (CHR) are a unique population enriched for precursors of major
psychiatric disorders, especially schizophrenia (SCZ). Recent neuroimaging findings point …

Volumetric assessment of individual thalamic nuclei in patients with drug-naïve, first-episode major depressive disorder

E Chibaatar, K Watanabe, N Okamoto… - Frontiers in …, 2023 - frontiersin.org
Introduction Despite the previous inconsistent findings of structural and functional
abnormalities of the thalamus in patients with major depressive disorder (MDD), the …

[HTML][HTML] Striatum and globus pallidus structural abnormalities in schizophrenia: a retrospective study of the different stages of the disease

Y Tang, Y Li, P Cao, Y Dong, G Xu, Q Si, R Li… - Progress in Neuro …, 2024 - Elsevier
Background The basal ganglia are important structures for the release of dopamine in the
limbic circuits of the midbrain, and the striatum and globus pallidus are the major nuclei of …

Evidence for decreased density of calretinin-immunopositive neurons in the caudate nucleus in patients with schizophrenia

I Adorjan, B Sun, V Feher, T Tyler, D Veres… - Frontiers in …, 2020 - frontiersin.org
Schizophrenia (SCH) and autism spectrum disorder (ASD) share several common
aetiological and symptomatic features suggesting they may be included in a common …