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Advances in the chemistry of tetrahydroquinolines
1.1. General Heterocyclic compounds, especially nitrogen heterocycles, are the most
important class of compounds in the pharmaceutical and agrochemical industries, with …
important class of compounds in the pharmaceutical and agrochemical industries, with …
[HTML][HTML] Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions
Ultrasound is an essential technique to improve organic synthesis from the point of view of
green chemistry, as it can promote better yields and selectivities, in addition to shorter …
green chemistry, as it can promote better yields and selectivities, in addition to shorter …
[HTML][HTML] Novel polyhydroquinoline-hydrazide-linked Schiff's base derivatives: multistep synthesis, antimicrobial, and calcium-channel-blocking activities
Polyhydroquinoline (PHQ) are the unsymmetrical Hantzsch derivatives of 1, 4-
dihydropyridines with several biological applications. In this work, twenty-five (3–27) new …
dihydropyridines with several biological applications. In this work, twenty-five (3–27) new …
Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
Novel polyhydroquinoline Schiff's base derivatives: synthesis, characterization, in vitro α-glucosidase inhibitory, and molecular docking studies
Novel Schiff's base hydrazone derivatives (1–24) based on polyhydroquinoline (PHQ) were
synthesized in good to excellent yields via three step reactions. Compound 1 (starting …
synthesized in good to excellent yields via three step reactions. Compound 1 (starting …
Immobilized ionic liquids on Fe3O4 nanoparticles: A potential catalyst for organic synthesis
Ionic liquids (ILs) are getting prominence as eco-sustainable solvents, especially as
alternatives to existing mediums in chemical reactions because of the advantage of …
alternatives to existing mediums in chemical reactions because of the advantage of …
Protein tyrosine phosphatase 1B (PTP1B) and obesity
H Cho - Vitamins & hormones, 2013 - Elsevier
Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of the leptin and insulin
signaling pathways. The important roles of PTP1B related to obesity and diabetes were …
signaling pathways. The important roles of PTP1B related to obesity and diabetes were …
[HTML][HTML] Cancer biology and prevention in diabetes
The available evidence suggests a complex relationship between diabetes and cancer.
Epidemiological data suggest a positive correlation, however, in certain types of cancer, a …
Epidemiological data suggest a positive correlation, however, in certain types of cancer, a …
One-Pot Sequential Synthesis of Alkenylated Dihydroquinolinones and Hexahydroacridinones in Deep Eutectic Solvent Medium
The sequential synthesis of N-heterocycles from saturated ketones poses significant
challenges and has rarely been reported. Herein, an efficient synthesis of alkenylated …
challenges and has rarely been reported. Herein, an efficient synthesis of alkenylated …
Synthesis of chalcones and flavanones using Julia–Kocienski olefination
A new application of Julia–Kocienski olefination for the synthesis of chalcones and
flavanones has been described. 2-(Benzo [d] thiazol-2-ylsulfonyl)-1-phenylethanones have …
flavanones has been described. 2-(Benzo [d] thiazol-2-ylsulfonyl)-1-phenylethanones have …