Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Approach to the patient with primary aldosteronism: utility and limitations of adrenal vein sampling

AF Turcu, R Auchus - The Journal of Clinical Endocrinology & …, 2021 - academic.oup.com
Several studies over the past 3 decades document a higher prevalence of primary
aldosteronism (PA) among hypertensive patients than generally presumed. PA exists as a …

Primary aldosteronism in patients in China with recently detected hypertension

Z Xu, J Yang, J Hu, Y Song, W He, T Luo… - Journal of the American …, 2020 - jacc.org
Abstract Background A total of 44.7% adults in China have hypertension, but the prevalence
of primary aldosteronism (PA) in Chinese hypertensive patients is unknown. Objectives This …

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Circulating extracellular vesicles as non-invasive biomarker of rejection in heart transplant

C Castellani, J Burrello, M Fedrigo, A Burrello… - The Journal of Heart and …, 2020 - Elsevier
Image, graphical abstract Download: Download high-res image (202KB) Download:
Download full-size image BACKGROUND Circulating extracellular vesicles (EVs) are …

Immune profiling of plasma-derived extracellular vesicles identifies Parkinson disease

E Vacchi, J Burrello, D Di Silvestre… - Neurology …, 2020 - AAN Enterprises
Objective To develop a diagnostic model based on plasma-derived extracellular vesicle
(EV) subpopulations in Parkinson disease (PD) and atypical parkinsonism (AP), we applied …

Development and validation of prediction models for subtype diagnosis of patients with primary aldosteronism

J Burrello, A Burrello, J Pieroni… - The Journal of …, 2020 - academic.oup.com
Context Primary aldosteronism (PA) comprises unilateral (lateralized [LPA]) and bilateral
disease (BPA). The identification of LPA is important to recommend potentially curative …

Primary aldosteronism and obstructive sleep apnea: a cross-sectional multi-ethnic study

F Buffolo, Q Li, S Monticone, DA Heinrich, A Mattei… - …, 2019 - Am Heart Assoc
The association between primary aldosteronism (PA) and obstructive sleep apnea (OSA)
has been a matter of debate. 2016 Endocrine Society guideline recommends screening for …

Mass spectrometry imaging establishes 2 distinct metabolic phenotypes of aldosterone-producing cell clusters in primary aldosteronism

N Sun, LS Meyer, A Feuchtinger, T Kunzke… - …, 2020 - Am Heart Assoc
Aldosterone-producing adenomas (APAs) are one of the main causes of primary
aldosteronism and the most prevalent surgically correctable form of hypertension …

Prevalence, diagnosis and outcomes of treatment for primary aldosteronism

Y Yang, M Reincke, TA Williams - Best Practice & Research Clinical …, 2020 - Elsevier
Primary aldosteronism (PA) is the most common potentially curable form of hypertension.
The overproduction of aldosterone leads to an increased risk of cardiovascular and …