Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or
diagnostic tools of high therapeutic value. However, only a handful have progressed to the …

Antimicrobial peptides are ubiquitous in multicellular organisms and have served as
defense mechanisms for their successful evolution and throughout their life cycle. These …

An infecting and propagating parasite relies on its innate defense system to evade the host's
immune response and to survive challenges from commensal bacteria. More so for the …

Antimicrobial peptides often show broad-spectrum activity due to a mechanism based on
bacterial membrane disruption, which also reduces development of permanent resistance, a …

Nature's way for bioactive peptides is to provide them with several related functions and the
ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as …

Antimicrobial peptides (AMPs) offer great hope and a promising opportunity to overcome the
rapid development of drug-resistant pathogenic microbes. However, AMPs often lack the …

Antibiotic resistance represents a significant challenge to public health and human safety.
The primary driver behind the dissemination of antibiotic resistance is the horizontal transfer …

Introduction: Low-molecular-weight antibiotics are gradually rendered ineffective by
multidrug-resistant bacteria. Promising replacements are fast-acting antimicrobial peptides …

Microorganism resistance to conventional antibiotics represents one of the major global
health concerns. This paper focuses on a peptide (OctoPartenopin) extracted from suckers …