Caffeine is consumed by over 80% of US adults. This review examines the effects caffeine
has on cognitive and physical function, since most real-world activities require complex …

Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

JCI - Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and
learning-dependent transcription Go to JCI Insight About Editors Consulting Editors For authors …

The hippocampus is critical for learning and memory, relying in part on pattern separation
processes supported by the dentate gyrus (DG) to prevent interference from overlap** …

The long-term fate of a memory is not exclusively determined by the events occurring at the
moment of encoding. Research at the cellular, circuit, and behavioral levels is beginning to …

This review provides details on the phytochemicals in green coffee beans and the changes
that occur during roasting. Key compounds in the coffee beverage, produced from the …

Coffee is the most frequently consumed caffeine-containing beverage. The caffeine in coffee
is a bioactive compound with stimulatory effects on the central nervous system and a …

Pattern separation, the ability to independently represent and store similar experiences, is a
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …

Caffeine (1, 3, 7-trimethylxanthine) is the most consumed psychoactive substance in the
world, acting by means of antagonism to adenosine receptors, mainly A1 and A2A. Coffee is …

The chemical composition of brewed coffee depends on numerous factors: the beans, post-
harvest processing and, finally, the extraction method. In recent decades, numerous coffee …