Simulation of nanopore sequencing signal data with tunable parameters
In silico simulation of high-throughput sequencing data is a technique used widely in the
genomics field. However, there is currently a lack of effective tools for creating simulated …
genomics field. However, there is currently a lack of effective tools for creating simulated …
Efficient real-time selective genome sequencing on resource-constrained devices
Background Third-generation nanopore sequencers offer selective sequencing or “Read
Until” that allows genomic reads to be analyzed in real time and abandoned halfway if not …
Until” that allows genomic reads to be analyzed in real time and abandoned halfway if not …
Accelerated nanopore basecalling with SLOW5 data format
Motivation Nanopore sequencing is emerging as a key pillar in the genomic technology
landscape but computational constraints limiting its scalability remain to be overcome. The …
landscape but computational constraints limiting its scalability remain to be overcome. The …
Flexible and efficient handling of nanopore sequencing signal data with slow5tools
Nanopore sequencing is being rapidly adopted in genomics. We recently developed
SLOW5, a new file format with advantages for storage and analysis of raw signal data from …
SLOW5, a new file format with advantages for storage and analysis of raw signal data from …
Accelerating genome analysis via algorithm-architecture co-design
High-throughput sequencing (HTS) technologies have revolutionized the field of genomics,
enabling rapid and cost-effective genome analysis for various applications. However, the …
enabling rapid and cost-effective genome analysis for various applications. However, the …
Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End
M Liu, J Li, CS Tan - Biosensors, 2023 - mdpi.com
The biomedical field has always fostered innovation and the development of various new
technologies. Beginning in the last century, demand for picoampere-level current detection …
technologies. Beginning in the last century, demand for picoampere-level current detection …
Squigulator: simulation of nanopore sequencing signal data with tunable noise parameters
In silico simulation of next-generation sequencing data is a technique used widely in the
genomics field. However, there is currently a lack of optimal tools for creating simulated data …
genomics field. However, there is currently a lack of optimal tools for creating simulated data …
RawHash2: map** raw nanopore signals using hash-based seeding and adaptive quantization
Raw nanopore signals can be analyzed while they are being generated, a process known
as real-time analysis. Real-time analysis of raw signals is essential to utilize the unique …
as real-time analysis. Real-time analysis of raw signals is essential to utilize the unique …
RawAlign: Accurate, fast, and scalable raw nanopore signal map** via combining seeding and alignment
Nanopore sequencers generate raw electrical signals representing the contents of a
biological sequence molecule passing through the nanopore. These signals can be …
biological sequence molecule passing through the nanopore. These signals can be …
Unveiling the Potential Pattern Representation of RNA 5-Methyluridine Modification Sites through a Novel Feature Fusion Model Leveraging Convolutional Neural …
The 5-Methyluridine (m5U), predominantly present in RNA and especially enriched in
transfer RNA (tRNA), significantly enhances translational accuracy and protein synthesis by …
transfer RNA (tRNA), significantly enhances translational accuracy and protein synthesis by …