Progress in corneal wound healing

AV Ljubimov, M Saghizadeh - Progress in retinal and eye research, 2015 - Elsevier
Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …

[HTML][HTML] Diabetic complications in the cornea

AV Ljubimov - Vision research, 2017 - Elsevier
Diabetic corneal alterations, such as delayed epithelial wound healing, edema, recurrent
erosions, neuropathy/loss of sensitivity, and tear film changes are frequent but …

Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds

EK White, A Uberoi, JTC Pan, JT Ort, AE Campbell… - Science …, 2024 - science.org
Chronic wounds are a common and costly complication of diabetes, where multifactorial
defects contribute to dysregulated skin repair, inflammation, tissue damage, and infection …

In-depth analysis of the human tear proteome

L Zhou, SZ Zhao, SK Koh, L Chen, C Vaz… - Journal of …, 2012 - Elsevier
The tears, a critical body fluid of the surface of the eye, contain an unknown number of
molecules including proteins/peptides, lipids, small molecule metabolites, and electrolytes …

Proteases, proteolysis and inflammatory molecules in the tears of people with keratoconus

SA Balasubramanian, S Mohan, DC Pye… - Acta …, 2012 - Wiley Online Library
Purpose: To investigate the expression of proteases, proteolytic activity and cytokines in the
tear film of people with keratoconus. Methods: Basal tears from people with keratoconus …

MMPs in the eye: emerging roles for matrix metalloproteinases in ocular physiology

JM Sivak, ME Fini - Progress in retinal and eye research, 2002 - Elsevier
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that function to
maintain and remodel tissue architecture. Their substrates represent an astounding variety …

Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological …

DT Azar - Transactions of the American Ophthalmological …, 2006 - pmc.ncbi.nlm.nih.gov
Purpose To determine the molecular basis of corneal avascularity during wound healing
and determine the role of angiogenic and antiangiogenic factors in corneal vasculogenesis …

Gene therapy in the anterior eye segment

C Amador, R Shah, S Ghiam, AA Kramerov… - Current gene …, 2022 - benthamdirect.com
This review provides comprehensive information about the advances in gene therapy in the
anterior segment of the eye, including cornea, conjunctiva, lacrimal gland, and trabecular …

Systemic diseases and the cornea

R Shah, C Amador, K Tormanen, S Ghiam… - Experimental eye …, 2021 - Elsevier
There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in …

PP Aung, N Oue, Y Mitani, H Nakayama, K Yoshida… - Oncogene, 2006 - nature.com
Gastric cancer (GC) is one of the most common malignancies worldwide. Genes expressed
only in cancer tissue will be useful molecular markers for diagnosis and may also be good …