Molecular pathways of major depressive disorder converge on the synapse

GR Fries, VA Saldana, J Finnstein, T Rein - Molecular Psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Diet and depression: exploring the biological mechanisms of action

W Marx, M Lane, M Hockey, H Aslam, M Berk… - Molecular …, 2021 - nature.com
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of …

HK Al-Hakeim, HT Al-Rubaye, DS Al-Hadrawi… - Molecular …, 2023 - nature.com
The immune-inflammatory response during the acute phase of COVID-19, as assessed
using peak body temperature (PBT) and peripheral oxygen saturation (SpO2), predicts the …

Mitochondrial dysfunction and neurological disorders: a narrative review and treatment overview

EE Alshial, MI Abdulghaney, AHS Wadan… - Life Sciences, 2023 - Elsevier
Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

[HTML][HTML] Mitochondrial dysfunction: a fatal blow in depression

Y Song, H Cao, C Zuo, Z Gu, Y Huang, J Miao… - Biomedicine & …, 2023 - Elsevier
Mitochondria maintain the normal physiological function of nerve cells by producing
sufficient cellular energy and performing crucial roles in maintaining the metabolic balance …

Nutritional psychiatry: the present state of the evidence

W Marx, G Moseley, M Berk, F Jacka - Proceedings of the Nutrition …, 2017 - cambridge.org
Mental illness, including depression, anxiety and bipolar disorder, accounts for a significant
proportion of global disability and poses a substantial social, economic and heath burden …

Peripheral markers of depression

A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

[HTML][HTML] Major depression: one brain, one disease, one set of intertwined processes

EV Filatova, MI Shadrina, PA Slominsky - Cells, 2021 - mdpi.com
Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …

Oxidative stress in Parkinson's disease: a systematic review and meta-analysis

Z Wei, X Li, X Li, Q Liu, Y Cheng - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Oxidative stress has been suggested to play a key role in Parkinson's disease, but
inconsistent results were found in clinical studies. This study sought to quantitatively …

The compensatory immune-regulatory reflex system (CIRS) in depression and bipolar disorder

M Maes, AF Carvalho - Molecular neurobiology, 2018 - Springer
Here, we review a novel concept namely the compensatory immune-regulatory reflex system
(CIRS) as applied to the pathophysiology of major depressive disorder (MDD) and bipolar …