The general secretory (Sec) pathway comprises an essential, ubiquitous and universal
export machinery for most proteins that integrate into, or translocate through, the plasma …

The microorganism Escherichia coli is commonly used for recombinant protein production.
Despite several advantageous characteristics like fast growth and high protein yields, its …

Acetogenic bacteria are a unique biocatalyst that highly promises to develop the sustainable
bioconversion of carbon oxides (eg, CO and CO2) into multicarbon biochemicals. Genotype …

Bacterial YidC, an evolutionally conserved membrane protein, functions as a membrane
protein chaperone in cooperation with the Sec translocon and as an independent insertase …

The spatial and temporal coordination of protein transport is an essential cornerstone of the
bacterial adaptation to different environmental conditions. By adjusting the protein …

The bacterial Sec translocase in its minimal form consists of a membrane-embedded protein-
conducting pore SecYEG that interacts with the motor protein SecA to mediate the …

The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In
prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor …

The YidC/Alb3/Oxa1 family functions in the insertion and folding of proteins in the bacterial
cytoplasmic membrane, the chloroplast thylakoid membrane, and the mitochondrial inner …

In Escherichia coli, proteins found in the periplasm or the outer membrane are exported from
the cytoplasm by the general secretory, Sec, system before they acquire stably folded …

Cytosolic metalloenzymes acquire metals from buffered intracellular pools. How exported
metalloenzymes are appropriately metalated is less clear. We provide evidence that TerC …