Revisiting immune checkpoint inhibitors: New strategies to enhance efficacy and reduce toxicity

D Zhang, J Zhao, Y Zhang, H Jiang, D Liu - Frontiers in Immunology, 2024 - frontiersin.org
In recent years, ICIs have transformed cancer treatment by harnessing the body's immune
system to target and destroy cancer cells (1–3). ICIs work by blocking inhibitory signals that …

Dual-Enzyme-Instructed Peptide Self-Assembly to Boost Immunogenic Cell Death by Coordinating Intracellular Calcium Overload and Chemotherapy

Z Zhang, Y Hu, Y Ding, X Zhang, X Dong, L **e… - ACS …, 2025 - ACS Publications
The concept of immunogenic cell death (ICD) induced by chemotherapy as a potential
synergistic modality for cancer immunotherapy has been widely discussed. Unfortunately …

Lung adenocarcinomas with mucinous histology: clinical, genomic, and immune microenvironment characterization and outcomes to immunotherapy-based …

A Di Federico, L Hong, A Elkrief, R Thummalapalli… - Annals of …, 2024 - Elsevier
Background Approximately 10% of lung adenocarcinomas (LUADs) have mucinous
histology (LUAD Muc), which is associated with a light/absent smoking history and a high …

Lipidomics reveals biomarkers of the efficacy of first-line ICIs therapy combined with chemotherapy in NSCLC

J Yu, H Xu, F **ong, L Meng, X Liu, H Gao, Y Li - 2024 - researchsquare.com
Immune checkpoint inhibitors (ICIs) plus chemotherapy have become the first-line standard
therapy for patients with the gene-negative advanced non-small cell lung cancer (NSCLC) …

[HTML][HTML] Jia Yu 1 Hanyan Xu 1 Fen **ong 2 Lingfei Meng 2 **ling Liu

H Gao, Y Li, H Gao, J Yu, H Xu - assets-eu.researchsquare.com
Immune checkpoint inhibitors (ICIs) plus chemotherapy have become the first-line standard
therapy for patients with the gene-negative advanced non-small cell lung cancer (NSCLC) …