Construction of Targeting-Peptide-Based Imaging Reagents and Their Application in Bioimaging

L Zhang, X Wang, J Zhao, B Sun… - Chemical & Biomedical …, 2023 - ACS Publications
Molecular imaging was developed from basic molecular recognition. It can visualize not only
the expression levels of specific molecules in a living system but also specific biological …

Bead-based screening in chemical biology and drug discovery

VV Komnatnyy, TE Nielsen, K Qvortrup - Chemical Communications, 2018 - pubs.rsc.org
High-throughput screening is an important component of the drug discovery process. The
screening of libraries containing hundreds of thousands of compounds requires assays …

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican

N von Spreckelsen, CM Fadzen… - Advanced …, 2021 - Wiley Online Library
Glioblastoma (GBM) is the most common and deadliest form of brain tumor and remains
amongst the most difficult cancers to treat. Brevican (Bcan), a central nervous system (CNS) …

A Rapid and Sensitive Salmonella Biosensor Based on Viscoelastic Inertial Microfluidics

L Yao, L Zheng, G Cai, S Wang, L Wang, J Lin - Sensors, 2020 - mdpi.com
Salmonella is a main cause of foodborne illnesses and rapid screening of Salmonella is the
key to prevent Salmonella outbreaks, however available detection methods either require a …

Developments with bead-based screening for novel drug discovery

D Pei, G Appiah Kubi - Expert opinion on drug discovery, 2019 - Taylor & Francis
Introduction: Combinatorial chemistry provides a cost-effective method for rapid discovery of
drug hits/leads. The one-bead-one-compound (OBOC) library method is in principle ideally …

Targeted Delivery Strategy of Indocyanine Green-Mitoxantrone Loaded Liposomes Co-Modified with BTP-7 and BR2 For the Treatment of Glioma

L **g, J Du, Y Dong, L Li, Z Tang, X Liu… - Pharmaceutical …, 2025 - Taylor & Francis
Objective This study aims to develop a dual-ligand-modified targeted drug delivery system
by integrating photosensitizers and chemotherapeutic drugs to enhance anti-glioma effects …

High-throughput approaches to the development of molecular imaging agents

LY Hu, KA Kelly, JL Sutcliffe - Molecular imaging and biology, 2017 - Springer
Molecular imaging allows for the visualization of changes at the cellular level in diseases
such as cancer. A successful molecular imaging agent must rely on disease-selective …

Placental exosomes viewed from an 'omics' perspective: implications for gestational diabetes biomarkers identification

AS Herrera-Van Oostdam… - Biomarkers in …, 2019 - Taylor & Francis
Exosomes are defined as extracellular vesicles that are released from cells upon fusion of
an intermediate endocytic compartment–the multivesicular body–with the plasma …

[PDF][PDF] Entwicklung von multidimensionalen Hochdurchsatzmethoden zur Analyse von Partikel-basierten Peptidbibliotheken

T Schwaar - 2020 - opus4.kobv.de
Gegenwärtig ist das Interesse und der Bedarf von Proteinbindern insbesondere in der
Biotechnik und Pharmaforschung sehr groß. Kombinatorische, Partikel-basierte (One-Bead …

[BOOK][B] Manipulation of Particles and Fluid with Surface Acoustic Waves

JS Tewksbury - 2021 - search.proquest.com
Small biomolecules can be challenging and expensive to isolate and manipulate, but they
may be the key for develo** more efficient diagnostic tools for the detection of biomarkers …