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Bioactive peptide of marine origin for the prevention and treatment of non-communicable diseases
R Pangestuti, SK Kim - Marine Drugs, 2017 - mdpi.com
Non-communicable diseases (NCD) are the leading cause of death and disability
worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers …
worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers …
Proteomic analysis reveals geographic variation in venom composition of Russell's Viper in the Indian subcontinent: Implications for clinical manifestations post …
ABSTRACT Introduction: The Russell's Viper (RV)(Daboia russelii), a category I medically
important snake, is responsible for a significant level of morbidity and mortality in the Indian …
important snake, is responsible for a significant level of morbidity and mortality in the Indian …
Proteomics and antivenomics of Echis carinatus carinatus venom: Correlation with pharmacological properties and pathophysiology of envenomation
The proteome composition of Echis carinatus carinatus venom (ECV) from India was studied
for the first time by tandem mass spectrometry analysis. A total of 90, 47, and 22 distinct …
for the first time by tandem mass spectrometry analysis. A total of 90, 47, and 22 distinct …
Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability
This study reports an efficient and convenient click chemistry synthesis of a novel series of
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …
Oxidative stress induced by Pollonein-LAAO, a new L-amino acid oxidase from Bothrops moojeni venom, prompts prostate tumor spheroid cell death and impairs the …
L Polloni, TR Costa, LP Morais, BC Borges… - Cellular …, 2023 - Elsevier
Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to
promote their malignant phenotype. In this framework, we hypothesized that the change in …
promote their malignant phenotype. In this framework, we hypothesized that the change in …
Snake venom toxins: Potential anticancer therapeutics
Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …
make up the toxin. The toxin components of snake venom attack several targets in the …
[HTML][HTML] Effects of animal venoms and toxins on hallmarks of cancer
Animal venoms are a cocktail of proteins and peptides, targeting vital physiological
processes. Venoms have evolved to assist in the capture and digestion of prey. Key venom …
processes. Venoms have evolved to assist in the capture and digestion of prey. Key venom …
Biosynthetic MnSe nanobomb with low Mn content activates the cGAS-STING pathway and induces immunogenic cell death to enhance antitumour immunity
W Gao, Y Wang, P Wang, W Kan, M Wang, H Li… - Acta Biomaterialia, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is a relatively “cold” tumour with low immunogenicity
compared to other tumour types. Especially, the immune checkpoint inhibitors to treat …
compared to other tumour types. Especially, the immune checkpoint inhibitors to treat …
Unraveling the proteome composition and immuno-profiling of western India Russell's viper venom for in-depth understanding of its pharmacological properties …
The proteome composition of western India (WI) Russell's viper venom (RVV) was correlated
with pharmacological properties and pathological manifestations of RV envenomation …
with pharmacological properties and pathological manifestations of RV envenomation …
A proteomic analysis of Pakistan Daboia russelii russelii venom and assessment of potency of Indian polyvalent and monovalent antivenom
To address the dearth of knowledge on the biochemical composition of Pakistan Russell's
Viper (Daboia russelii russelii) venom (RVV), the venom proteome has been analyzed and …
Viper (Daboia russelii russelii) venom (RVV), the venom proteome has been analyzed and …