Chemokines are chemotactic cytokines which recruit leukocytes to inflammatory sites. They
also affect tumor development and metastasis by acting as growth factor, by attracting pro-or …

MALDIquant is an R package providing a complete and modular analysis pipeline for
quantitative analysis of mass spectrometry data. MALDIquant is specifically designed with …

Purpose Complete resection constitutes the only curative approach in pancreatic cancer but
is possible only in a minority of patients due to advanced stages upon diagnosis …

Objective Current non-invasive diagnostic tests can distinguish between pancreatic cancer
(pancreatic ductal adenocarcinoma (PDAC)) and chronic pancreatitis (CP) in only about two …

Background: To improve the prognosis of patients with pancreatic cancer, more accurate
serum diagnostic methods are required. We used serum metabolomics as a diagnostic …

Exercise training reduces the incidence of several cancers, but the mechanisms underlying
these effects are not fully understood. Exercise training can affect the spleen function, which …

Mass spectrometry-based serum metabolic profiling is a promising tool to analyse complex
cancer associated metabolic alterations, which may broaden our pathophysiological …

Pancreatic cancer is an aggressive disease with poor prognosis, due, in part, to the lack of
disease-specific biomarkers that could afford early and accurate diagnosis. With a …

Exosomes are nanosized vesicles commonly found in biological fluids as a result of a
secretion process involving endosomes and multivesicular bodies. The isolation and …

Patients with pancreatic cancer (PC) are usually diagnosed at late stages, when the disease
is nearly incurable. Sensitive and specific markers are critical for supporting diagnostic and …