Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH)
superfamily of transcription factors, which are associated with cellular responses to …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor recognized for
its role in xenobiotic metabolism. The physiologic function of AHR has expanded to include …

The induction of expression of genes for xenobiotic metabolizing enzymes in response to
chemical insult is an adaptive response found in most organisms. In vertebrates, the AhR is …

Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that …

Axelrod et al.(1958) first described the enzyme-catalyzed O-methylation of catecholamines
and other catechols in the late 1950s. The enzyme responsible for the O-methylation …

The primary design of this perspective is to describe the major ligand classes of the aryl
hydrocarbon receptor (AHR). A grander objective is to provide models that may help define …

Cytochrome P450 enzymes that metabolize estrogens are expressed in the mammary
gland, uterus, brain and other target tissues for estrogen action, and this results in the …

The lower incidences of many chronic diseases such as cancer and cardiovascular related
ailments are associated with consumption of vegetables rich dietary regimes and this has …

The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …

Introduction The oncoprotective role of food-derived polyphenol antioxidants has been
described but the implicated mechanisms are not yet clear. In addition to polyphenols …