Regular exercise offers protection against all-cause mortality, primarily by protection against
cardiovascular disease and Type 2 diabetes mellitus. The latter disorders have been …

Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …

Many physiological changes occur with aging. These changes often, directly or indirectly,
result in a deterioration of the quality of life and even in a shortening of life expectancy …

Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state.
Hyperinsulinemia and insulin action were initially proposed as the common preceding …

Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …

Studies have demonstrated that circulating levels of plasma cytokines are influenced greatly
by age and that chronic elevated levels of certain cytokines are associated with chronic …

This article reviews the rapidly accumulating literature on the relationship between mood
disorders and diabetes mellitus. Recent studies have demonstrated that depression and its …

To monitor inflammation in a meaningful way, the markers used must be valid: they must
reflect the inflammatory process under study and they must be predictive of future health …

Aging is associated with increased inflammatory activity reflected by increased circulating
levels of TNF-α, IL-6, cytokine antagonists and acute phase proteins in vivo. Epidemiologic …