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Synthetic biology: bottom-up assembly of molecular systems
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …
opportunities to engineer artificial vesicular systems for applications with previously unmet …
The time and place for nature in drug discovery
The case for a renewed focus on Nature in drug discovery is reviewed; not in terms of
natural product screening, but how and why biomimetic molecules, especially those …
natural product screening, but how and why biomimetic molecules, especially those …
Expanding the synthetic toolbox through metal–enzyme cascade reactions
The combination of metal-, photo-, enzyme-, and/or organocatalysis provides multiple
synthetic solutions, especially when the creation of chiral centers is involved. Historically …
synthetic solutions, especially when the creation of chiral centers is involved. Historically …
Biomimetic metallic nanostructures for biomedical applications, catalysis, and beyond
MT Yaraki, S Zahed Nasab, I Zare… - Industrial & …, 2022 - ACS Publications
Nature has inspired scientists to develop green and sustainable nanomaterials with
biomimetic functions. Particularly, biomimetic metallic nanostructures (biometal NPs) with …
biomimetic functions. Particularly, biomimetic metallic nanostructures (biometal NPs) with …
Hydrolase mimic via second coordination sphere engineering in metal-organic frameworks for environmental remediation
X Yuan, X Wu, J **ong, B Yan, R Gao, S Liu… - Nature …, 2023 - nature.com
Enzymes achieve high catalytic activity with their elaborate arrangements of amino acid
residues in confined optimized spaces. Nevertheless, when exposed to complicated …
residues in confined optimized spaces. Nevertheless, when exposed to complicated …
Recent advances in biocatalysis with chemical modification and expanded amino acid alphabet
The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …
have found widespread applications in improving the intrinsic activities of proteins. Although …
Noncanonical Amino Acids: Bringing New-to-Nature Functionalities to Biocatalysis
Biocatalysis has become an important component of modern organic chemistry, presenting
an efficient and environmentally friendly approach to synthetic transformations. Advances in …
an efficient and environmentally friendly approach to synthetic transformations. Advances in …
Nanoscale chemical reaction exploration with a quantum magnifying glass
Nanoscopic systems exhibit diverse molecular substructures by which they facilitate specific
functions. Theoretical models of them, which aim at describing, understanding, and …
functions. Theoretical models of them, which aim at describing, understanding, and …
Learning from protein engineering by deconvolution of multi‐mutational variants
This review analyzes a development in biochemistry, enzymology and biotechnology that
originally came as a surprise. Following the establishment of directed evolution of …
originally came as a surprise. Following the establishment of directed evolution of …
Quaternary charge-transfer complex enables photoenzymatic intermolecular hydroalkylation of olefins
Intermolecular C–C bond-forming reactions are underdeveloped transformations in the field
of biocatalysis. Here we report a photoenzymatic intermolecular hydroalkylation of olefins …
of biocatalysis. Here we report a photoenzymatic intermolecular hydroalkylation of olefins …