MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …

Background Genetic, environmental and epigenetical factors may play important roles in the
pathogenesis of polycystic ovary syndrome (PCOS), however the etiology of PCOS remains …

Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in females of
the reproductive age. PCOS is commonly manifested as ovulatory dysfunction, clinical and …

Female aging is one of the most important factors that impacts human reproduction. With
aging, there is a natural decline in female fertility. The decrease in fertility is slow and steady …

Objective: MicroRNAs (miRNAs) are gene expression regulators. Altered miRNA levels are
associated with diabetes, insulin resistance, and inflammation. Insulin resistance and …

MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of
post-transcriptional gene expression during tissue development and differentiation. They are …

The genetic regulation of female fertility (follicular development, oocyte maturation and early
preimplantation embryo development) involves the spatio-temporal regulation of those …

Follicular fluid is one source of microRNAs (miRNAs). These miRNAs originate from oocytes
and their neighboring cells. The changes in the miRNAs profile in the follicular fluid could …

MicroRNAs (miRNAs) are secreted from cells as either protein-bound or enclosed in
extracellular vesicles. Circulating liver-derived miRNAs are modifiable by weight-loss or …

Background: Women with polycystic ovary syndrome (PCOS) often change their metabolic
profile over time to decrease levels of androgens while often gaining a propensity for the …